Successful treatment of an aggressive recurrent post-menopausal endometriosis with an aromatase inhibitor

Fatemi HM, H M Fatemi, Al-Turki HA, H A Al-Turki, HA Al-Turki, Papanikolaou EG, EG Papanikolaou, E G Papanikolaou, L Kosmas, Kosmas L, De Sutter P, P. De Sutter, Devroey P, Paul Devroey, P. Devroey
Reproductive BioMedicine Online · 2005 · vol. 11(4) , pp. 455–457 · doi:10.1016/s1472-6483(10)61140-6 · PMID:16274608 · W2073503248
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This paper reports the successful treatment of a patient with aggressive recurrent post-menopausal endometriosis using an aromatase inhibitor.

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Abstract

The current case report describes the development and medical treatment of an aggressive pelvic endometrioma in a post-menopausal patient, who had undergone abdominal hysterectomy and salpingo-oophorectomy a decade earlier. The patient was referred to the authors' centre because of right-sided sciatic pain. Three months before her admission she was hospitalized elsewhere due to subacute bowel obstruction. She was operated on and a resection of a part of sigmoid colon and an endometrioma, which was the cause of the subobstruction, was carried out. During the clinical investigation for the right-sided sciatic pain, an intrapelvic mass was found, which was compressing the lumbo-sacral plexus mimicking sciatica. The diagnosis of recurrent endometrioma was confirmed by a computerized tomography-guided biopsy and the decision was made to treat it with an aromatase inhibitor (letrozole). Eighteen months later, the endometrioma was almost completely regressed and the patient was free of symptoms. Medical management of recurrent post-menopausal endometriosis with aromatase inhibitors seems to be an effective alternative treatment to surgery.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Aromatase Inhibitors Aromatase Inhibitors Colon, Sigmoid Colon, Sigmoid Endometriosis Endometriosis Female Humans Hysterectomy Letrozole Middle Aged Nitriles Nitriles Postmenopause Recurrence Sciatica Sciatica Time Factors Treatment Outcome

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (48)

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