Aromatasehemmer in der Therapie der Endometriose
This review elucidates the role of aromatase in endometriosis pathogenesis and evaluates aromatase inhibitors as a potential treatment option.
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This review examines the role of aromatase in the pathogenesis of endometriosis and summarizes existing clinical experience with aromatase inhibitors as potential therapies. It discusses that standard endometriosis treatment aims for a hypoestrogenic state using agents such as progestins, gestagen-focused contraceptives, GnRH analogues, and danazol, and notes limitations including insufficient symptom relief, recurrence, and side effects in some patients. The paper’s key conclusion is that aromatase inhibitors may represent an alternative therapeutic option based on new research linking aromatase to endometriosis biology, while the overall caveat is that the evidence is framed as “current insights” and “clinical experience,” without providing a single definitive trial result within the review text. This paper is centrally about endometriosis — it focuses on aromatase biology and aromatase inhibitors as a treatment option for endometriosis.
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