Ovarian cancer remains one of the leading causes of cancer-related deaths in women. There are several processes that are described to have a causal relationship in ovarian cancer development, progression, and metastasis formation, that occu…
Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female reproductive tract causing high morbidity as they can significantly affect fertility and quality of life. Adipokines are pleiotropic signaling molecules …
BackgroundEstrogen receptor (ER) β has been suggested to affect ovarian carcinogenesis. We examined the effects of four ERβ agonists on proliferation and gene expression of two ovarian cancer cell lines.MethodsOVCAR-3 and OAW-42 ovarian can…
BackgroundThe role of estrogen receptor beta (ERβ) in pathogenesis of endometriosis remains to be elucidated. In this study, we have examined the expression of the four main ERβ transcript isoforms in human endometrial tissue in women with …
Einleitung: Die Rolle von Östrogenrezeptor beta (ERß) in der Pathogenese der Endometriose wird in der Literatur zunehmend diskutiert. Ziel unserer Arbeit ist es, neben der Expression von ERα die zyklische Expression von ERß und v.a. seiner …
In der Endometrioseforschung gilt die Chorioallantoismembran (CAM) als mögliches Modell zum Studium der Implantation des Endometriums. Eine wichtige Voraussetzung für die Implantation ist die Angiogenese, welche einer komplexen Steuerung du…