Role of Aromatase Inhibitors in the Treatment of Endometriosis

Ercan Baştu
In: Annals of Clinical and Analytical Medicine · 2014 · vol. 05(Suppl_2) · doi:10.4328/jcam.2782 · W2188343235
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This review evaluates aromatase inhibitors as a potential treatment for endometriosis by examining their role in regulating estrogen production and impacting the disease.

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Abstract

Endometriosis is a chronic gynecologic disease that is defined by the existence of ectopic glands and stroma outside the uterine cavity. Some hormonal therapies have been suggested to treat pain that is caused be endometriosis. The basic premise behind these hormonal therapies is that they inhibit the production of estrogens in the ovary. However, some patients can still suffer from pain despite the usage of these conventional hormonal therapies. Aromatase activity is involved in the levels of protein expression, enzyme activity and transcriptional expression in endometriosis. Hence, several researchers have investigated and evaluated aromatase inhibitors (AIs) as a potential treatment option for endometriosis. This aim of this review is to evaluate the role of aromatase inhibitors in the treatment of endometriosis.

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Condition tags

endometriosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (45)

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