Letrozole and norethisterone acetate in rectovaginal endometriosis
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This study investigated the efficacy and safety of letrozole and norethisterone acetate for treating rectovaginal endometriosis.
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Abstract
This open-label prospective study evaluated the efficacy of letrozole (2.5 mg/day) combined with norethisterone acetate (2.5 mg/day) in the treatment of pain symptoms related to the presence of rectovaginal endometriosis. The treatment significantly and quickly decreased the intensity of symptoms, but pain recurred at 3-month follow-up; five women underwent surgery during the follow-up, and histologic examination of rectovaginal nodules revealed the presence of active endometriotic lesions.
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References (5)
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- Multislice CT enteroclysis in the diagnosis of bowel endometriosis via openalex
- The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial via openalex
- Treatment of symptomatic rectovaginal endometriosis with an estrogen–progestogen combination versus low-dose norethindrone acetate via openalex
- W2159803441 via openalex
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- Traitement de l’endométriose par les inhibiteurs de l’aromatase : efficacité thérapeutique et conséquences osseuses 2010
- Current pharmacotherapy for endometriosis 2010
- Aromatase inhibitors in the treatment of deep endometriosis 2009
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- last seen: 2026-07-27T06:15:28.040536+00:00
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- pubmed
- last seen: 2026-05-13T22:15:00.519696+00:00
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