Endometriosis of the Appendix: When to Predict and How to Manage-A Multivariate Analysis of 1935 Endometriosis Cases

Mabrouk M, Mohamed Mabrouk, Raimondo D, Diego Raimondo, Manuela Mastronardi, Raimondo I, Ivano Raimondo, Simona Del Forno, Arena A, Alessandro Arena, Neveta Sutherland, Sutherland N, Borgia A, Alessandra Borgia, Mattioli G, Giulia Mattioli, Patrizia Terzano, Terzano P, Renato Seracchioli
Journal of Minimally Invasive Gynecology · 2019 · vol. 27(1) , pp. 100–106 · doi:10.1016/j.jmig.2019.02.015 · PMID:30849476 · W2919771793
Observational OA: green CC0 ⤵ 40 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-06 ⓘ

This study analyzes 1935 endometriosis cases to identify predictors of appendiceal endometriosis and outline optimal management strategies.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

STUDY OBJECTIVE: To evaluate appendiceal endometriosis (AE) prevalence and risk factors in endometriotic patients submitted to surgery. DESIGN: A retrospective cohort study. SETTING: A tertiary level referral center, university hospital. PATIENTS: One thousand nine hundred thirty-five consecutive patients who underwent surgical removal for symptomatic endometriosis. INTERVENTIONS: Electronic medical records of patients submitted to surgery over a 12-year period were reviewed. We assessed any correlation between demographic, clinical, and surgical variables and AE. In our center, appendectomy was performed using a selective approach. Appendix removal was performed in case of gross abnormalities of the organ, such as enlargement, dilation, tortuosity, or discoloration of the organ or the presence of suspected endometriotic implants. MEASUREMENTS AND MAIN RESULTS: AE prevalence was 2.6% (50/1935), with only 1 false-positive case at gross intraoperative evaluation. In multivariate analysis using a stepwise logistic regression model, independent risk factors for AE were adenomyosis (adjusted odds ratio [aOR] = 2.48; 95% confidence interval [CI], 1.32-4.68), right endometrioma (aOR = 8.03; 95% CI, 4.08-15.80), right endometrioma ≥5 cm (aOR = 13.90; 95% CI, 6.63-29.15), bladder endometriosis (aOR = 2.05; 95% CI, 1.05-3.99), deep posterior pelvic endometriosis (aOR = 5.79; 95% CI, 2.82-11.90), left deep lateral pelvic endometriosis (aOR = 2.11; 95% CI, 1.10-4.02), and ileocecal involvement (aOR = 12.51; 95% CI, 2.07-75.75). CONCLUSION: Among patients with endometriosis submitted to surgery, AE was observed in 2.6%, and it was associated with adenomyosis, large right endometrioma, bladder endometriosis, deep posterior pelvic endometriosis, left deep lateral pelvic endometriosis, and ileocecal involvement.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Appendix Cecal Diseases Cecal Diseases Endometriosis Endometriosis Adult Adult Appendectomy Appendectomy Appendectomy Appendectomy Appendectomy Appendix Appendix Cecal Diseases Cecal Diseases Cecal Diseases Cohort Studies Cohort Studies Endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (41)

Cited by (41)

Source provenance

europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:24:09.876621+00:00
License: CC0 · commercial use OK