Risk of appendiceal endometriosis among women with deep‐infiltrating endometriosis

Janelle K Moulder, Matthew T Siedhoff, Kathryn L Melvin, Kathryn Melvin, Elizabeth G Jarvis, K.A. Hobbs, Kumari A Hobbs, Joanne M. Garrett, Joanne Garrett
International Journal of Gynecology & Obstetrics · 2017 · vol. 139(2) , pp. 149–154 · doi:10.1002/ijgo.12286 · PMID:28755505 · W2740342922
article OA: closed CC0 ⤵ 29 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This retrospective study found that women with deep-infiltrating endometriosis had a significantly higher risk of appendiceal endometriosis compared to those with superficial endometriosis or no endometriosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVE: To determine whether deep-infiltrating endometriosis (DE) carries an increased risk of appendiceal endometriosis (AppE) as compared with superficial endometriosis or no endometriosis. METHODS: In a retrospective study, data were obtained by chart review of an internal database for women who underwent coincidental appendectomy during benign gynecologic surgery between July 2009 and February 2014 at a tertiary referral center in the USA. Univariate, bivariate, and regression analyses were performed. The primary exposure was surgically documented endometriosis (DE, superficial, or no endometriosis). The primary outcome was AppE. RESULTS: Endometriosis was diagnosed for 151 (38.2%) of 395 women; 82 (54.3%) had DE. The prevalence of AppE was 13.2% (52/395) overall; 8 (11.6%) of 69 women with superficial endometriosis and 32 (39.0%) of 82 with DE were affected. Frequency of AppE was increased among women with DE, abnormal appendix appearance, and surgical indication (all P<0.001). Women with DE had a 5.9-fold (95% confidence interval [CI] 2.9-11.9) higher risk of AppE compared with women without endometriosis, controlling for appendiceal appearance and surgical indication, and a 2.7-fold (95% CI 1.2-6.2) higher risk of AppE compared with those with superficial endometriosis. CONCLUSION: Women with DE have increased risk of AppE. Coincidental appendectomy should form part of complete endometriosis excision for these patients.

My notes (saved in your browser only)

Condition tags

mesh:D004715endometriosis

MeSH descriptors

Appendix Cecal Diseases Endometriosis Adult Appendectomy Cecal Diseases Cecal Diseases Cecal Diseases Databases, Factual Endometriosis Endometriosis Endometriosis Female Humans North Carolina North Carolina Prevalence Referral and Consultation Retrospective Studies Risk Factors

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (23)

Cited by (29)

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:20:19.560968+00:00
unpaywall
last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0 · commercial use OK