Surgical treatment of endometriosis: a prospective randomized double-blinded trial comparing excision and ablation

Healey M, Martin Healey, W Catarina Ang, Claudia Cheng
Fertility and sterility · 2010 · vol. 94(7) , pp. 2536–2540 · doi:10.1016/j.fertnstert.2010.02.044 · PMID:20356588 · W1979264303
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This prospective randomized double-blinded trial compared surgical excision and ablation for treating endometriosis, evaluating their respective outcomes.

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Abstract

ObjectiveTo compare reduction of pain following laparoscopy after ablation or excision of endometriosis.DesignA prospective, randomized, double-blind study.SettingEndometriosis and pelvic pain clinic at a university teaching hospital.Patient(s)Women of reproductive age presenting with pelvic pain and visually proved endometriosis.Intervention(s)Subjects completed a questionnaire rating their various pains using visual analogue scales (VASs). After visual identification subjects were assigned randomly to treatment with ablation or excision by supervised training gynecologists as primary surgeon. Follow-up questionnaires at 3, 6, 9, and 12 months documented pain levels.Main outcome measure(s)Change in overall pain VAS score at 12 months after operation.Result(s)There was no significant difference in reduction in overall pain VAS scores at 12 months when comparing ablation and excision.Conclusion(s)This study has not been able to demonstrate a significant difference in pain reduction between ablation and excisional treatments. Nonsignificant trends suggest that a larger study may find a difference in outcomes looking at dyspareunia or dyschezia.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Gynecologic Surgical Procedures Muscular Diseases Ablation Techniques Ablation Techniques Ablation Techniques Adult Algorithms Double-Blind Method Endometriosis Female Gynecologic Surgical Procedures Gynecologic Surgical Procedures Humans Laparoscopy Laparoscopy Muscular Diseases Rectal Diseases Rectal Diseases Surveys and Questionnaires

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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