Endometriosis and Infertility: An Enigma

J C WEED, John C. Weed, Weed Jc, Holland JB, J B Holland, John Holland
Fertility and sterility · 1977 · vol. 28(2) , pp. 135–140 · doi:10.1016/s0015-0282(16)42370-8 · PMID:832723 · W2202725803
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This review explores the complex and often enigmatic relationship between endometriosis and infertility, discussing potential pathophysiological mechanisms and diagnostic challenges.

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Abstract

In our efforts to overcome infertility and subjective complaints in young women with endometriosis, we have performed conservative surgical procedures upon 142 women 30 years of age or less. In these women, multiple endometriomata were resected from the pelvic peritoneum, one or both ovaries, the large and small bowel, and the appendix. In addition, uterine and ovarian suspension, bowel resection, appendectomy, myomectomy, and presacral neurectomy (PSN) were performed when indicated. Conception occurred in 70% of the women wishing to conceive; the highest rate was found among those who had developed endometriosis after a previous conception. Ovarian involvement seemed to reduce the conception rate by 10%. Uterine suspension and PSN did not affect conception but did provide a symptomatic relief. We conclude that early examination for endometriosis and aggressive surgical management is indicated in young women with demonstrable disease.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Infertility, Female Pelvic Neoplasms Adolescent Adult Endometriosis Endometriosis Endometriosis Female Humans Hysterectomy Infertility, Female Infertility, Female Infertility, Female Ovary Ovary Ovary Pelvic Neoplasms Pelvic Neoplasms Pelvic Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (16)

Cited by (10)

Source provenance

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