Affected sib-pair analysis in endometriosis
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⤵ 38 in-corpus citations
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This paper reviews genetic evidence for endometriosis and outlines the affected-sib pair analysis approach used in the OXEGENE study to identify disease susceptibility genes.
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Abstract
This paper (i) reviews the current clinical and molecular genetic data which strongly suggest that endometriosis has a genetic basis; (ii) outlines the general principles of affected-sib pair analysis; and (iii) describes the Oxford Endometriosis Gene (OXEGENE) Study which aims, using a positional cloning approach, to identify susceptibility genes involved in the development of the disease.
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Cited by (38)
- The quest for genetic sequence variants conferring risk of endometriosis 2020
- Endometriosis, Cytological Findings 2017
- Differentially expressed genes: OCT-4, SOX2, STAT3, CDH1 and CDH2, in cultured mesenchymal stem cells challenged with serum of women with endometriosis 2017
- Evaluation of Risk Factors Associated with Endometriosis in Infertile Women 2016
- Reproductive prognosis in daughters of women with and without endometriosis 2013
- Tumor necrosis factor and interleukin-6 gene polymorphisms and endometriosis risk in Asians: a systematic review and meta-analysis 2013
- Replication of endometriosis-associated single-nucleotide polymorphisms from genome-wide association studies in a Caucasian population 2013
- Association of endometriosis risk and genetic polymorphisms involving biosynthesis of sex steroids and their receptors: an updating meta-analysis 2012
- Endometriosis 2012
- Pathogenesis of endometriosis: the role of genetics, inflammation and oxidative stress 2012
- Genetic Polymorphisms and Molecular Pathogenesis of Endometriosis 2012
- Genetic variation in the sex hormone metabolic pathway and endometriosis risk: an evaluation of candidate genes 2011
- Pathophysiological factors and genetic association in endometriosis 2011
- Ovarian cancer-associated polymorphisms in the BNC2 gene among women with endometriosis 2011
- Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1 2010
- Differential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis 2010
- Rectovaginal septum endometriosis: an immunohistochemical analysis of 62 cases 2009
- Endometriosis: pathogenesis, diagnosis, therapy and association with cancer (review) 2008
- Endometriosis 2008
- Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis 2008
- Tumor necrosis factor (TNF)-TNF receptor gene polymorphisms and their serum levels in Korean women with endometriosis 2008
- Why do they do it? A pilot study towards understanding participant motivation and experience in a large genetic epidemiological study of endometriosis 2007
- Differences in characteristics among 1,000 women with endometriosis based on extent of disease 2007
- Where are the genes that cause endometriosis? 2005
- Endometriosis: new genetic approaches and therapy 2005
- Quantitative DNA perturbations of p53 in endometriosis: analysis of American and Icelandic cases 2005
- Lack of association between endometriosis and the CYP17 MspA1 polymorphism in UK and Japanese populations 2005
- Association between human alpha 2-Heremans Schmidt glycoprotein (AHSG) polymorphism and endometriosis in Korean women 2004
- Genetic basis of endometriosis 2004
- Serum and endometrial markers 2004
- Endometriosis 2004
- The tumor necrosis factor-alpha promoter -1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population 2004
- Heritability and candidate genes for endometriosis 2003
- Genetics of Endometriosis 2003
- Genetics of endometriosis 2003
- Molecular approach to common causes of female infertility 2002
- The genetic epidemiology of spontaneous endometriosis in the rhesus monkey 2002
- High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis 2002
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