Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1

Sundqvist J, Johanna Sundqvist, Henrik Falconer, Seddighzadeh M, Maria Seddighzadeh, Alexandra Vodolazkaia, Vodolazkaia A, Fassbender A, Amelie Fassbender, Cleophas Kyama, Bokor A, Attila Bokor, Olof Stephansson, Leonid Padyukov, Gemzell-Danielsson K, Kristina Gemzell‐Danielsson, Kristina Gemzell-Danielsson, Thomas D'Hooghe, Thomas D’Hooghe, Thomas M D'Hooghe, D'Hooghe TM
Fertility and sterility · 2010 · vol. 95(1) , pp. 437–440 · doi:10.1016/j.fertnstert.2010.07.1060 · PMID:20797713 · W2052197964
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This paper investigated the association between moderate/severe endometriosis and the immune system, finding links with CCL21 and HLA-DRB1.

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Abstract

This study investigates the association of rheumatoid arthritis-associated single nucleotide polymorphisms in endometriosis. We found an association of CCL21 (rs2812378) and HLA-DRB1 (rs660895) with moderate to severe endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Autoimmune Diseases Autoimmune Diseases Autoimmune Diseases Autoimmune Diseases Chemokine CCL21 Endometriosis Endometriosis Endometriosis Endometriosis HLA-DR Antigens Adult Chemokine CCL21 Female Genetic Predisposition to Disease Genetic Predisposition to Disease HLA-DR Antigens HLA-DRB1 Chains Humans Polymorphism, Single Nucleotide Severity of Illness Index

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (43)

Cited by (35)

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