Diagnostic accuracy of transvaginal sonography for the diagnosis of adenomyosis: systematic review and metaanalysis

Susanna M Meredith, Meredith SM, Susanna Meredith, Luis Sanchez‐Ramos, Sanchez-Ramos L, Luis Sanchez-Ramos, Andrew M. Kaunitz, Kaunitz AM
American journal of obstetrics and gynecology · 2009 · vol. 201(1) , pp. 107.e1–107.e6 · doi:10.1016/j.ajog.2009.03.021 · PMID:19398089 · W1967830496
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This systematic review and meta-analysis evaluated the diagnostic accuracy of transvaginal sonography for identifying adenomyosis.

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Abstract

ObjectiveThe purpose of this study was to critically appraise the diagnostic accuracy of transvaginal sonography for diagnosing adenomyosis.Study designComputerized databases were used to identify relevant reports published between 1966 and 2007 reporting data on the accuracy of transvaginal sonography for diagnosing adenomyosis in women having hysterectomy. The presence or absence of adenomyosis was confirmed by histopathologic analysis of hysterectomy specimens. The total analysis included 14 trials with 1895 aggregate participants. Two authors independently assessed methodological quality and constructed tables for the assessment of diagnostic measures.ResultsTransvaginal ultrasound predicted adenomyosis with a likelihood ratio of 4.67 (95% confidence interval [CI], 3.13-6.17). The overall prevalence of adenomyosis was 27.9% (95% CI, 25.5-30.3). The probability of adenomyosis with an abnormal transvaginal ultrasound was 66.2% (95% CI, 61.6- 70.6). The probability of adenomyosis with a normal transvaginal ultrasound was 9.1% (95% CI, 7.3-11.1).ConclusionTransvaginal sonography appears to be an accurate diagnostic test for adenomyosis.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Area Under Curve Endometriosis Endometriosis Endosonography Endosonography Female Humans Likelihood Functions Pregnancy Sensitivity and Specificity Vagina Vagina

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (50)

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