Adenomyosis interferes with accurate ultrasonographic detection of uterine leiomyomas

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Adenomyosis was the most common diagnosis in women with inaccurate ultrasonographic detection of uterine leiomyomas, affecting both false-positive and false-negative results.

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This study evaluated the diagnostic accuracy of preoperative pelvic ultrasonography for uterine leiomyomas by comparing ultrasound findings with postoperative pathology in 333 women who underwent hysterectomy for pelvic pain, menorrhagia and/or leiomyomas, with an ultrasound performed within 1 year before surgery. Ultrasound showed high sensitivity (95.9%) but low specificity (42.5%), with positive and negative predictive values of 92.4% and 58.6%, respectively, and a large proportion of both false-positive (70.8%) and false-negative (83.3%) results occurring in women with adenomyosis. Previous pelvic surgery and higher body mass index were also common in women with inaccurate ultrasound findings. This paper is centrally about endometriosis and adenomyosis — it specifically demonstrates that adenomyosis interferes with accurate ultrasonographic detection of uterine leiomyomas.

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Abstract

ObjectiveTo evaluate the accuracy of pelvic ultrasonography, and the characteristics of women with inaccurate ultrasonographic diagnosis for uterine leiomyomas.Materials and methodsPreoperative pelvic ultrasonographic and postoperative pathologic findings of all women, who underwent hysterectomies for pelvic pain, menorrhagia and/or leiomyomas between December 1995 and July 2002, were evaluated. Three hundred thirty-three women, who had a transabdominal or transvaginal pelvic ultrasonography within 1 year prior to the hysterectomy, were included in the study. We assessed the accuracy of ultrasonography for uterine leiomyomas in this group, and defined the characteristics of women with inaccurate studies.ResultsDespite its high sensitivity (95.9%), ultrasonography had only 42.5% specificity for detecting leiomyomas. Its positive predictive and the negative predictive values were 92.4% and 58.6%, respectively. Adenomyosis was found in the majority of the women with false-positive (70.8%) and false-negative (83.3%) results. In both groups, previous pelvic surgery and high body mass index (BMI) were also common.ConclusionAdenomyosis is the most common final diagnosis in women with inaccurate ultrasound reports for uterine leiomyomas.
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Abstract

Objective: To evaluate the accuracy of pelvic ultrasonography, and the characteristics of women with inaccurate ultrasonographic diagnosis for uterine leiomyomas. Materials and methods: Preoperative pelvic ultrasonographic and postoperative pathologic findings of all women, who underwent hysterectomies for pelvic pain, menorrhagia and/or leiomyomas between December 1995 and July 2002, were evaluated. Three hundred thirty-three women, who had a transabdominal or transvaginal pelvic ultrasonography within 1 year prior to the hysterectomy, were included in the study. We assessed the accuracy of ultrasonography for uterine leiomyomas in this group, and defined the characteristics of women with inaccurate studies. Results: Despite its high sensitivity (95.9%), ultrasonography had only 42.5% specificity for detecting leiomyomas. Its positive predictive and the negative predictive values were 92.4% and 58.6%, respectively. Adenomyosis was found in the majority of the women with false-positive (70.8%) and false-negative (83.3%) results. In both groups, previous pelvic surgery and high body mass index (BMI) were also common. Conclusion: Adenomyosis is the most common final diagnosis in women with inaccurate ultrasound reports for uterine leiomyomas. Similar content being viewed by others

References

Marshall LM, Spiegelman D, Barbieri RL, Goldman MB, Manson JE, Colditz GA, Willett WC, Hunter DJ (1997) Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol 90:967–973 Caoili EM, Hertzberg BS, Kliewer MA, DeLong D, Bowie JD (2000) Refractory shadowing from pelvic masses on sonography: a useful diagnostic sign for uterine leiomyomata. AJR 174:97–101 Leibman AJ, Kruse B, McSweeney MB (1988) Transvaginal sonography: comparison with transabdominal sonography in the diagnosis of pelvic masses. AJR 151:89–92 Mendelson EB, Bohm-Velez M, Joseph N, Neiman HL (1988) Gynecologic imaging: comparison of transabdominal and transvaginal sonography. Radiology 166:321–324 Fedele L, Bianchi S, Dorta M, Zanotti F, Brioschi D, Carinelli S (1992) Transvaginal ultrasonography in the differential diagnosis of adenoleiomyoma versus leiomyoma. Am J Obstet Gynecol 167:603–606 Cicinelli E, Romano F, Anastasio PS, Blasi N, Parisi C, Galantino P (1995) Transabdominal sonohysterography, transvaginal sonography, and hysteroscopy in the evaluation of submucous leiomyomata. Obstet Gynecol 85:42–47 Dueholm M, Lundorf E, Hansen ES, Ledertoug S, Olesen F (2002) Accuracy of magnetic resonance imaging and transvaginal ultrasonography in the diagnosis, mapping, and measurement of uterine leiomyomata. Am J Obstet Gynecol 186:409–415 Karasick S, Lev-Toaff AS, Toaff ME (1992) Imaging of uterine leiomyomas. AJR 158:799–805 Dudiak CM, Turner DA, Patel SK, Archie JT, Silver B, Norusis M (1988) Uterine leiomyomata in the infertility patient: preoperative localization with MR imaging versus US and hysterosalpingography. Radiology 167:627–630 Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Harmanli, O.H., Bevilacqua, S.A., Dandolu, V. et al. Adenomyosis interferes with accurate ultrasonographic detection of uterine leiomyomas. Arch Gynecol Obstet 273, 146–149 (2005). https://doi.org/10.1007/s00404-005-0037-7 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-005-0037-7

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Leiomyoma Uterine Diseases Adult Aged Endometriosis Endometriosis Female Humans Leiomyoma Leiomyoma Middle Aged Pennsylvania Pennsylvania Predictive Value of Tests Sensitivity and Specificity Ultrasonography Uterine Diseases Uterine Diseases Uterine Neoplasms

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