Benign Myometrial Conditions: Leiomyomas and Adenomyosis

Ascher SM, Susan M Ascher, Reena Jha, Reena C Jha, Jha RC, Reinhold C, Caroline Reinhold
Topics in magnetic resonance imaging : TMRI · 2003 · vol. 14(4) , pp. 281–304 · doi:10.1097/00002142-200308000-00003 · PMID:14578775 · W2074533801
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Magnetic resonance imaging accurately diagnoses uterine leiomyomas and adenomyosis by identifying lesion number, size, and location, guiding therapeutic decisions for these common benign myometrial conditions.

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Abstract

Leiomyomas and adenomyosis are common benign myometrial conditions. Although their symptoms overlap, traditional treatment of these two entities differs; thus, making the correct diagnosis is critical. Specifically, uterine-conserving therapy is well established for many women with symptomatic leiomyomas, whereas hysterectomy is the treatment for debilitating adenomyosis. Magnetic resonance imaging (MRI) is the most accurate modality for identifying leiomyomas and adenomyosis. T2-weighted sequences often are diagnostic. For leiomyomas, MRI reliably identifies their number, size, and location. These features help triage patients to appropriate therapy. For adenomyosis, MRI establishes the diagnosis in cases of equivocal or nondiagnostic ultrasounds. MRI also has been used to confirm an ultrasound diagnosis of adenomyosis when curative surgery is being considered. Intravenous gadolinium chelates are not necessary to make the diagnosis of either adenomyosis or leiomyomas, but it provides useful information about vascularity of lesions, a factor that may impact the type of treatment undertaken.
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Benign Myometrial Conditions: Leiomyomas and Adenomyosis - Susan M. Ascher - Reena C. Jha - Caroline Reinhold Summary: Leiomyomas and adenomyosis are common benign myometrial conditions. Although their symptoms overlap, traditional treatment of these two entities differs; thus, making the correct diagnosis is critical. Specifically, uterine-conserving therapy is well established for many women with symptomatic leiomyomas, whereas hysterectomy is the treatment for debilitating adenomyosis. Magnetic resonance imaging (MRI) is the most accurate modality for identifying leiomyomas and adenomyosis. T2-weighted sequences often are diagnostic. For leiomyomas, MRI reliably identifies their number, size, and location. These features help triage patients to appropriate therapy. For adenomyosis, MRI establishes the diagnosis in cases of equivocal or nondiagnostic ultrasounds. MRI also has been used to confirm an ultrasound diagnosis of adenomyosis when curative surgery is being considered. Intravenous gadolinium chelates are not necessary to make the diagnosis of either adenomyosis or leiomyomas, but it provides useful information about vascularity of lesions, a factor that may impact the type of treatment undertaken.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Leiomyoma Magnetic Resonance Imaging Magnetic Resonance Imaging Uterine Neoplasms Contrast Media Diagnosis, Differential Endometriosis Female Gadolinium Humans Image Enhancement Image Enhancement Leiomyoma Leiomyoma Practice Guidelines as Topic Sensitivity and Specificity Uterine Neoplasms Uterine Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (52)

Cited by (27)

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