Diffusion-weighted imaging (DWI) of adenomyosis and fibroids of the uterus

Reena C Jha, Reena Jha, Paulo A Zanello, Susan M Ascher, Sunder Rajan, Sunder S. Rajan
Abdominal imaging · 2014 · vol. 39(3) , pp. 562–569 · doi:10.1007/s00261-014-0095-z · PMID:24531353 · W1990191192
article OA: closed CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This study evaluated differences in apparent diffusion coefficient (ADC) values between uterine fibroids and adenomyosis, finding statistically significant distinctions and less heterogeneity in adenomyosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This retrospective study compared diffusion-weighted MRI apparent diffusion coefficient (ADC) values between uterine fibroids and adenomyosis in 50 patients who underwent pelvic MR imaging, using b factors of 50, 400, and 800 s/mm on a 1.5 T scanner. ADC regions of interest were measured in fibroid tissue, adenomyosis areas, normal myometrium, skeletal muscle, and urine, and histogram analysis in subsets (20 cases each) assessed tissue heterogeneity. Adenomyosis and fibroids showed statistically significant ADC differences versus normal myometrium and versus each other (adenomyosis mean 0.86 ± 0.30 vs fibroids 0.64 ± 0.29 × 10−3 mm2/s), and histogram analysis indicated less heterogeneity in adenomyosis than in fibroids, with the main caveat being that ADC differentiation was studied retrospectively without explicit histopathologic confirmation details in the abstract. This paper is centrally about endometriosis and/or adenomyosis — specifically adenomyosis imaging differentiation from fibroids using quantitative DWI/ADC measurements.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Diffusion Magnetic Resonance Imaging Leiomyoma Myometrium Uterine Neoplasms Uterus Adenomyosis Adult Diagnosis, Differential Diffusion Magnetic Resonance Imaging Female Humans Leiomyoma Myometrium Phantoms, Imaging Reproducibility of Results Retrospective Studies Uterine Neoplasms Uterus

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