Adenomyosis and leiomyoma: differential diagnosis with MR imaging.
article
OA: closed
CC0
⤵ 102 in-corpus citations
AI-generated summary
MR imaging correctly diagnosed all eight cases of adenomyosis by identifying junctional zone thickening or poorly marginated low-signal-intensity masses.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
To assess the capability of magnetic resonance (MR) imaging to enable differentiation of adenomyosis from leiomyoma, a prospective study was performed in 21 premenopausal patients with a strong clinical suggestion of adenomyosis. Histologic findings from hysterectomy (19 patients) and biopsy specimens (two patients) showed that eight patients had adenomyosis (three focal, five diffuse) and 12 had leiomyomas (five of the 12 also had microscopic foci of adenomyosis); one patient had a normal uterus. All eight cases of adenomyosis were correctly diagnosed from MR images. On T2-weighted MR images, diffuse adenomyosis appeared as a thickening of the junctional zone, whereas focal adenomyosis appeared as a low-signal-intensity mass poorly marginated from the adjacent myometrium. Ten of the 12 leiomyomas were correctly diagnosed from MR images. In the other two cases of leiomyoma, differentiation between focal adenomyosis and leiomyoma was not possible. Microscopic foci of adenomyosis were not demonstrated with MR imaging.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
Cited by (50)
- Three-dimensional modeling and intraoperative navigation in the diagnosis and treatment of various forms of adenomyosis 2025
- Differential Diagnosis of Uterine Fibroids and Adenomyosis 2025
- Comprehensive Review of Endometriosis Based on Imaging Findings: What Radiologists Need to Know 2025
- Efficacy of MRI Over Ultrasound in Evaluation of Abnormal Uterine Bleeding With Histopathological Correlation 2023
- Correlation between MRI Features of Adenomyosis and Clinical Presentation 2023
- A method for isolating and culturing ectopic epithelial and stromal cells to study human adenomyosis 2023
- A method for isolating and culturing ectopic epithelial and stromal cells to study human adenomyosis 2023
- Investigation and management of abnormal uterine bleeding in reproductive-aged women: a descriptive review of national and international recommendations 2022
- In Search of an Imaging Classification of Adenomyosis: A Role for Elastography? 2022
- Uterine Embolization as a New Treatment Option in Adenomyosis Uteri 2022
- Unveiling the Pathogenesis of Adenomyosis through Animal Models 2022
- Diffusion‐weighted imaging of uterine adenomyosis: Correlation with clinical backgrounds and comparison with malignant uterine tumors 2021
- Endometriosis - Recent Advances, New Perspectives and Treatments 2021
- Activation of the cGAS–STING signaling pathway in adenomyosis patients 2021
- Classifying Adenomyosis: Progress and Challenges 2021
- TAS/TVS versus histopathological diagnosis in abnormal uterine bleeding: A comparative study 2020
- MRI as an imaging tool in abnormal uterine bleeding among no gravid women 2020
- Classification and Reporting Systems for Adenomyosis 2019
- Influences of screening magnetic resonance imaging parameters on high-intensity focused ultrasound outcome for adenomyosis 2018
- Phenotypic characterization of adenomyosis occurring at the inner and outer myometrium 2017
- Improving Ultrasound Detection of Uterine Adenomyosis Through Computational Texture Analysis 2017
- The benefit of adenomyomectomy on fertility outcomes in women with rectovaginal endometriosis with coexisting adenomyosis 2016
- The Incidence and Clinical Significance of Adenomyosis 2015
- The Pathophysiology of Adenomyosis 2015
- The Role of the Myometrium in Adenomyosis 2015
- Who will benefit from uterus-sparing surgery in adenomyosis-associated subfertility? 2014
- Diagnóstico de la adenomiosis 2014
- Benign Diseases of the Uterus 2014
- Pelvic Imaging in Reproductive Endocrinology 2013
- The pathophysiology of uterine adenomyosis: an update 2012
- Patients with adenomyosis are more likely to have deep endometriosis 2012
- Future developments in the medical treatment of abnormal uterine bleeding 2011
- FIGO classification system (PALM‐COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age 2011
- Phenotypic Characterisation of the Inner and Outer Myometrium in Normal and Adenomyotic Uteri 2010
- Adenomiose em pacientes com endometriose profunda: aspectos clínicos, histológicos e radiológicos 2010
- Ultrasound scan and magnetic resonance imaging for the diagnosis of adenomyosis: systematic review comparing test accuracy 2010
- Benign Diseases of the Female Genital Tract 2010
- Pelvic Imaging in Reproductive Endocrinology 2009
- Adenomyosis uteri: an update 2009
- Adenomyosis: New Knowledge is Generating New Treatment Strategies 2009
- Adenomyosis and ‘endometrial– subendometrial myometrium unit disruption disease’ are two different entities 2008
- Adenomyose 2008
- Uterine adenomyosis: a need for uniform terminology and consensus classification 2008
- Adenomyosis 2007
- Uterine innervation in adenomyosis 2007
- Transvaginal ultrasound or MRI for diagnosis of adenomyosis 2007
- Utero‐Tubal Sperm Transport and Its Impairment in Endometriosis and Adenomyosis 2007
- Predictive value of magnetic resonance imaging in differentiating between leiomyoma and adenomyosis. 2007
- MRI of Adenomyosis: Changes with Uterine Artery Embolization 2006
- Uterotubal transport disorder in adenomyosis and endometriosis—a cause for infertility 2006
Source provenance
- europepmc
- last seen: 2026-08-08T06:08:32.324769+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:09:30.565292+00:00
- unpaywall
- last seen: 2026-08-07T06:39:35.550527+00:00
License: CC0
· commercial use OK