The Role of the Myometrium in Adenomyosis

Classically adenomyosis is defined by the presence of ectopic endometrial glands surrounded by ‘hyperplastic-hypertrophic myometrium’. Whilst there remains disagreement on the definition and diagnostic criteria, the diagnosis of adenomyosis by modern imaging relies on the identification of features that distinguish the inner from the outer myometrium. There are demonstrable differences between the inner and outer layers of the myometrium as well as differences between uteri with and without adenmyosis. Myometrial changes have long been regarded as a response to invasion by the endometrium but more recent literature raises the possibility that the myometrium may have a role in the pathogenesis of adenomyosis, perhaps because of innate predisposition. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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