{"paper_id":"6f3cce14-cf18-4182-9c69-683dbe8cf490","body_text":"Abstract\nClassically adenomyosis is defined by the presence of ectopic endometrial glands surrounded by ‘hyperplastic-hypertrophic myometrium’. Whilst there remains disagreement on the definition and diagnostic criteria, the diagnosis of adenomyosis by modern imaging relies on the identification of features that distinguish the inner from the outer myometrium. There are demonstrable differences between the inner and outer layers of the myometrium as well as differences between uteri with and without adenmyosis. Myometrial changes have long been regarded as a response to invasion by the endometrium but more recent literature raises the possibility that the myometrium may have a role in the pathogenesis of adenomyosis, perhaps because of innate predisposition.\nAccess this chapter\nTax calculation will be finalised at checkout\nPurchases are for personal use only\nSimilar content being viewed by others\nReferences\nBird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterus – revisited. Am J Obstet Gynecol. 1972;112:583–93.\nCullen TS. Adenomyoma of the uterus. Philadelphia/London: W.B. Saunders Company; 1908.\nNovak ER, Woodruff JD. Adenomyosis (adenomyoma) uteri. In: Novak's gynecologic and obstetric pathology. Philadelphia: W.B. Saunders Company; 1979. p. 280–90.\nHendrickson MR, Kempson RL. Non-neoplastic conditions of the myometrium and uterine serosa. In: Surgical pathology of the uterine corpus. Philadelphia: W.B. Saunders; 1980.\nLanglois PL. 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Springer, Cham. https://doi.org/10.1007/978-3-319-13012-5_5\nDownload citation\nDOI: https://doi.org/10.1007/978-3-319-13012-5_5\nPublished:\nPublisher Name: Springer, Cham\nPrint ISBN: 978-3-319-13011-8\nOnline ISBN: 978-3-319-13012-5\neBook Packages: MedicineMedicine (R0)","source_license":"CC0","license_restricted":false}