MR imaging in the evaluation of benign uterine masses: value of gadopentetate dimeglumine-enhanced T1-weighted images.

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Contrast-enhanced T1-weighted MR images did not improve detection or characterization of uterine leiomyomas or adenomyosis but significantly improved endometrial polyp detection.

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Abstract

Forty-six patients with surgically proved disease (115 leiomyomas, 19 cases of adenomyosis, and 14 endometrial polyps) were studied to determine if gadopentetate dimeglumine-enhanced T1-weighted MR images improve the detection and characterization of benign tumors of the uterus. Lesion detection and characterization were assessed separately for each sequence (unenhanced T1-weighted, proton-density-weighted, and T2-weighted and contrast-enhanced T1-weighted images) and for combinations of sequences (unenhanced T1- and T2-weighted images, unenhanced and contrast-enhanced T1-weighted images, and unenhanced T1- and T2-weighted and contrast-enhanced T1-weighted images). In the evaluation of leiomyomas, analysis of all three sequences provided the best detection (92%) and characterization (92%), but the improvement, except when compared with unenhanced T1-weighted images alone, was not statistically significant. The use of contrast medium did not contribute to either tumor detection or characterization. In the evaluation of adenomyosis, T2-weighted images provided significantly better lesion detection and characterization than did either unenhanced or contrast-enhanced T1-weighted images. In the evaluation of endometrial polyps, however, contrast-enhanced T1-weighted images provided significantly better lesion detection and characterization than did unenhanced images. With contrast-enhanced images, the detection rate was 79%, compared with 36% for T2-weighted images and 7% for T1-weighted images. Lesion characterization was the best (73%) when all imaging sequences were analyzed. Our study shows that with conventional spin-echo sequences, the use of contrast-enhanced T1-weighted images does not improve the detection or characterization of uterine leiomyomas or adenomyosis but significantly improves the detection of endometrial polyps.

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Condition tags

mesh:D004715adenomyosis

MeSH descriptors

Endometrial Neoplasms Endometriosis Leiomyoma Magnetic Resonance Imaging Polyps Uterine Neoplasms Contrast Media Drug Combinations Endometrial Neoplasms Endometriosis Female Gadolinium Gadolinium DTPA Humans Leiomyoma Magnetic Resonance Imaging Meglumine Middle Aged Organometallic Compounds Pentetic Acid

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
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