Efficacy of high intensity focused ultrasound treatment for cystic adenomyosis: a report of four cases

Xiaojing Zhou, Xiao-Jing Zhou, Zhiming Zhao, Zhi-Ming Zhao, Peng Liu, Congying Zhao, Cong-Ying Zhao, Yu-Jie Lin, Ying Liu, Min Wang, Cai Tian, Tian Cai, Haiyan Li, Hai-Yan Li, Chen-Xiao Hou, Chenxiao Hou, Xiu-Min Li, Xiumin Li, Zhi-Yu Zhao, Zhiyu Zhao, Yingjie Zhou, Ying-Jie Zhou
Annals of palliative medicine · 2020 · vol. 9(6) , pp. 3742–3749 · doi:10.21037/apm-20-1599 · PMID:33302646 · W3109733747
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Abstract

BACKGROUND: Cystic adenomyosis is a particular type of adenomyosis, High intensity focused ultrasound (HIFU), as a non-invasive method, has also been used to treat adenomyosis. The purpose of this study was to investigate the efficacy, safety, and feasibility of HIFU for the treatment of cystic adenomyosis. METHODS: Diagnosis of cystic adenomyosis was obtained through trans-vaginal ultrasound and magnetic resonance imaging (MRI). Ultrasound-guided HIFU ablation was performed under conscious sedation. The patients were evaluated by the comparison of pre-HIFU and post-HIFU imaging, as well as the Uterine Fibroid Symptom and Quality of Life (UFS-QOL) questionnaire subscales, consisting of Symptom Severity Score (SSS) and Heath Related Quality of Life (HRQL). RESULTS: HIFU was effective in treating cystic adenomyosis. No complications were observed in the four patients who were successfully treated with HIFU. Compared to preoperative symptoms and patient satisfaction, symptoms at the first follow-up observed significant improvements, with no dysmenorrhea and high health-related quality of life. During the outpatient follow-up of one month, three months, and six months postoperation, the four patients were still without dysmenorrhea and were highly satisfied with the HIFU ablation. CONCLUSIONS: HIFU, as a non-invasive treatment, supplies a safe and effective possibility for the treatment of cystic adenomyosis.

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Condition tags

adenomyosisdysmenorrhea

MeSH descriptors

Adenomyosis Adenomyosis High-Intensity Focused Ultrasound Ablation Leiomyoma Leiomyoma Female Humans Quality of Life Treatment Outcome

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