Pathologic Findings from the Maryland Womenʼs Health Study: Practice Patterns in the Diagnosis of Adenomyosis

J D Seidman, Jeffrey D. Seidman, Seidman JD, K H Kjerulff, Kjerulff KH, Kristen H. Kjerulff
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists · 1996 · vol. 15(3) , pp. 217–221 · doi:10.1097/00004347-199607000-00005 · PMID:8811382 · W2032087175
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Review of 1252 hysterectomy pathology reports revealed wide variation in adenomyosis diagnosis frequency (12-58% across hospitals, 10-88% across pathologists) not explained by patient age or parity.

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Abstract

Criteria for the diagnosis of adenomyosis vary widely in practice. The reported frequency of adenomyosis in hysterectomy specimens varies from 5-70% in published series. In this study, 1252 pathology reports on hysterectomy specimens from women enrolled in the Maryland Women's Health Study were reviewed. The frequency of adenomyosis was calculated based on two subgroups: 1114 reports from 15 hospitals, and 705 reports signed by 25 pathologists. The frequency of diagnosis of adenomyosis ranged from 12% to 58% among the 15 hospitals, and 10% to 88% among the 25 pathologists. This wide variation could not be explained by differences in patient age or number of pregnancies, factors known to correlate with the frequency of adenomyosis. These data suggest that adenomyosis may be overdiagnosed. Stringent and widely accepted criteria for the diagnosis of adenomyosis are needed, as epidemiologic studies of this common condition would be facilitated by the use of standard criteria in practice.
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Pathologic Findings from the Maryland Women's Health Study: Practice Patterns in the Diagnosis of Adenomyosis - Jeffrey D. Seidman - Kristen H. Kjerulff Summary: Criteria for the diagnosis of adenomyosis vary widely in practice. The reported frequency of adenomyosis in hysterectomy specimens varies from 5–70% in published series. In this study, 1252 pathology reports on hysterectomy specimens from women enrolled in the Maryland Women's Health Study were reviewed. The frequency of adenomyosis was calculated based on two subgroups: 1114 reports from 15 hospitals, and 705 reports signed by 25 pathologists. The frequency of diagnosis of adenomyosis ranged from 12% to 58% among the 15 hospitals, and 10% to 88% among the 25 pathologists. This wide variation could not be explained by differences in patient age or number of pregnancies, factors known to correlate with the frequency of adenomyosis. These data suggest that adenomyosis may be overdiagnosed. Stringent and widely accepted criteria for the diagnosis of adenomyosis are needed, as epidemiologic studies of this common condition would be facilitated by the use of standard criteria in practice.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Endometriosis Pathology, Surgical Practice Patterns, Physicians' Uterine Diseases Adult Endometriosis Female Health Surveys Humans Maryland Maryland Middle Aged Pathology, Surgical Uterine Diseases

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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