The clinical significance of classical and new emerging determinants of adenomyosis.

Serkan Bodur, Ozgur Dundar, Özgür Dündar, Mine Kanat Pektas, Mine Kanat-Pektaş, Mustafa Alparslan Babayiğit, Mustafa Alparslan Babayigit, Okan Özden, Okan Ozden, Zafer Kucukodacı, Zafer Küçükodacı
International journal of clinical and experimental medicine · 2015 · vol. 8(5) , pp. 7958–64 · PMID:26221354 · PMC4509299 · W2415776592
article OA: green CC0 ⤵ 8 in-corpus citations
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This study analyzed clinical characteristics and mean platelet volume in 99 women undergoing hysterectomy, finding that younger age, higher parity, curettages, dysmenorrhea, and elevated mean platelet volume were associated with adenomyosis.

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Abstract

OBJECTIVE: The present study aims to analyze the diagnostic accuracy of clinical characteristics together with new emerging laboratory markers of adenomyosis. METHODS: This study was a retrospective analysis of clinical and laboratory characteristics of 99 women who underwent hysterectomies with (study group) or without (control group) a diagnosis of adenomyosis, 56 and 43 patients in each group, respectively. RESULTS: The women with adenomyosis were more likely to have younger age (OR = 1.14, 0.789-0.971 95% CI, P = 0.010), higher parity (OR = 1.81, 0.308-0.988 95% CI, P = 0.046), higher number of curettage (OR = 1.90, 1.189-3.041 95% CI, P = 0.007), dysmenorrhea (OR = 117.49, 2.715-5084.883 95% CI, P = 0.013) and elevated mean platelet volume (OR = 5.17, 2.054-13.028 95% CI, P = 0.000). After receiver-operating-characteristics curve analysis, using a cut-point of 8.5 fL, the preoperative mean platelet volume predicted adenomyosis with a sensitivity of 56.6% and specificity of 82.6%. CONCLUSIONS: Those findings suggest gynecologists to give priority on adenomyosis when premenopausal paraous patient with a history of curettages admitted with a complaint of dysmenorrhea and elevated levels of MPV.

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adenomyosisdysmenorrhea

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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