Optimal Management of Endometriosis and Pain

Camran Nezhat, Vang N, Nataliya Vang, Pedro Tanaka, Pedro P Tanaka, Nezhat C, Ceana Nezhat
Obstetrics and gynecology · 2019 · vol. 134(4) , pp. 834–839 · doi:10.1097/aog.0000000000003461 · PMID:31503153 · W2972808623
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Optimal management of endometriosis-associated pain involves egg preservation, preoperative medical suppression, and modified postoperative hormonal suppression based on disease severity and fertility goals.

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Abstract

The pathophysiology of endometriosis-associated pain involves inflammatory and hormonal alterations and changes in brain signaling pathways. Although medical treatment can provide temporary relief, most patients can achieve long-term sustained pain relief when it is combined with surgical intervention. Owing to its complexity, there is an ongoing debate about how to optimally manage endometriosis-associated pain. We believe optimal management for this condition requires: 1) possible egg preservation in affected young patients with and without endometriomas; 2) preoperative medical suppression to inhibit ovulation and to avoid removal of functional cysts that might look like endometriomas; and 3) postoperative hormonal suppression to decrease recurrence, but this treatment should be modified according to disease severity, symptoms, and fertility goals.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Pelvic Pain Endometriosis Endometriosis Endometriosis Female Female Gynecologic Surgical Procedures Gynecologic Surgical Procedures Humans Humans Pelvic Pain Pelvic Pain Pelvic Pain

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (26)

Cited by (50)

Source provenance

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