Additional file 2 of Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis

Su, Wenliang, Cui, Huan, Wu, Danning, Yu, Jiawen, Ma, Lulu, Zhang, Xiuhua, Huang, Yuguang, Ma, Chao
2021 · doi:10.6084/m9.figshare.14173925 · W6902032955
other OA: green CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Uterus horn excision in rats did not induce mechanical pain or alter key inflammatory markers in the gastrocnemius muscle, indicating this procedure alone does not cause the pain studied.

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Abstract

Additional file 2: Fig. S2 The excision of uterus horn tissue did not induced mechanical pain at the gastrocnemius muscle. A. The time course of mechanical threshold at the gastrocnemius muscle for rats receiving the excision of uterus horn or not. N=8 in each group, Two-way ANOVA followed by Bonferroni's post-hoc test. B-C. The expression of HMGB1, TLR4, MyD88 and pNF-κB-p65 was not altered by the excision of uterus horn tissue. N=4, One-way ANOVA followed by Bonferroni's post-hoc test.

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endometriosis

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