Optimal Management of Endometriosis and Pain

Camran Nezhat, Nataliya Vang, Pedro P Tanaka, Pedro Tanaka, Ceana Nezhat
Obstetrics and gynecology · 2019 · vol. 134(4) , pp. 834–839 · doi:10.1097/aog.0000000000003461 · PMID:31503153 · W2972808623
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⚙ AI-generated summary by claude@2026-06, 2026-06-04 ⓘ

Optimal management of endometriosis-associated pain involves egg preservation, preoperative medical suppression, and modified postoperative hormonal suppression based on disease severity and fertility goals.

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Abstract

The pathophysiology of endometriosis-associated pain involves inflammatory and hormonal alterations and changes in brain signaling pathways. Although medical treatment can provide temporary relief, most patients can achieve long-term sustained pain relief when it is combined with surgical intervention. Owing to its complexity, there is an ongoing debate about how to optimally manage endometriosis-associated pain. We believe optimal management for this condition requires: 1) possible egg preservation in affected young patients with and without endometriomas; 2) preoperative medical suppression to inhibit ovulation and to avoid removal of functional cysts that might look like endometriomas; and 3) postoperative hormonal suppression to decrease recurrence, but this treatment should be modified according to disease severity, symptoms, and fertility goals.

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Pelvic Pain Endometriosis Endometriosis Female Gynecologic Surgical Procedures Humans Pelvic Pain Pelvic Pain

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (26)

Cited by (50)

Source provenance

europepmc
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openalex
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