Yasushi Hirota
No ORCID on file
· 137 papers in corpus
· active 2002-2026
Study types
- article 106
- other 15
- preprint 5
- book-chapter 4
- review 4
Condition tags
- endometriosis 101
- adenomyosis 36
- endometrioma 27
- infertility 12
- dysmenorrhea 8
- mesh:D004716 2
- thoracic_endometriosis 1
- die_deep_infiltrating 1
- disambig:endometritis 1
- chronic_pelvic_pain 1
Top journals
Frequent coauthors
- Yutaka Osuga 132
- Kaori Koga 101
- Miyuki Harada 92
- Tomoyuki Hirata 91
- Osamu Yoshino 48
- Tomoyuki Fujii 46
- Yojiro Taketani 45
- Osamu Wada-Hiraike 44
- Gentaro Izumi 41
- Masashi Takamura 39
article
2015
article
2015
case-report
2015
STUDY OBJECTIVES: To evaluate the frequency of pneumothorax after laparoscopic surgery and to identify possible correlations to endometriosis. DESIGN: Retrospective review. SETTING: Tokyo University Hospital between 2006 and 2013. PATIEN…
article
2015
article
2015
article
2015
PROBLEM: The proportion of CD4+ T lymphocytes, Th1, Th2, Th17, and regulatory T cells in endometriosis lesions and peripheral blood are not known. METHOD OF STUDY: Lymphocytes were isolated from endometriosis lesions (n = 10) and endometriu…
article
2014
Dienogest is a novel progestin that is highly selective for progesterone receptors and inhibits endometriosis. However, it remains unknown how the administration of dienogest to patients with endometriosis impacts on their lesion tissues. T…
article
2014
Adenomyosis is a common disorder in premenopausal women that causes dysmenorrhea, pelvic pain and menorrhagia. Considering that adenomyosis is an estrogen-dependent disease, the medical treatment is based on this hormone. Effective and well…
article
2014
PROBLEM: Immune tolerance to endometriotic cells is important to promote endometriosis. Tryptophan 2,3-dioxygenase (TDO) enhances immune tolerance by catabolizing tryptophan to kynurenine. We studied whether interleukin-1β (IL-1β), a typica…
book-chapter
2014
article
2014
article
2014
article
2013
article
2013
CONTEXT: Endometriosis is a chronic inflammatory disease in which immune response and production of estrogen in endometriotic tissues are involved in the development of the disease. Prostaglandin E2 (PGE2) stimulates aromatase (P450arom) ex…
article
2013
book-chapter
2012
article
2012
article
2012
article
2012
STUDY QUESTION: Is thymic stromal lymphopoietin (TSLP) involved in the pathophysiology of endometriosis? SUMMARY ANSWER: TSLP is up-regulated by interleukin (IL)-1β and may be involved in the development of endometriosis. WHAT IS KNOWN ALRE…
review
2012
Proteinase-activated receptors (PARs) are G protein-coupled receptors activated by various proteinases. PARs play important roles in haemostasis, thrombosis, and inflammation. PAR1 and PAR2 are expressed in endometrial cells from the eutopi…
article
2012
Proteinase-activated receptors (PARs) are G protein-coupled receptors activated by various proteinases. PARs play important roles in haemostasis, thrombosis, and inflammation. PAR₁ and PAR₂ are expressed in endometrial cells from the eutopi…
article
2011
article
2011
article
2011
BACKGROUND: Proteinase-activated receptor 2 (PAR2) is a G-protein-coupled receptor that is activated by several serine proteases. PAR2 activation in endometriotic stromal cells (ESCs) has been implicated in the development of endometriosis …
review
2010
Endometriosis is a disease characterized by the presence of endometriotic tissue outside the uterine cavity. Although its pathogenesis remains to be elucidated, immune status is suggested to play an important role in the initiation and the …