Journal of Obstetrics and Gynaecology Research

PURPOSE: To investigate the association between dendritic cell maturation deficits and pain in patients with adenomyosis and explore potential neuro-immune mechanisms. METHODS: Uterine tissues from 24 patients with adenomyosis (AM) and 15 …

AIM: To investigate the differences in lipid metabolism and obesity between patients with ovarian endometrioid carcinoma (OEC) and ovarian clear cell carcinoma (OCCC), both of which are classified as endometriosis-associated Type I ovarian …

AIM: To evaluate the incidence of tubo-ovarian abscess (TOA) in patients with ovarian endometrioma (OE) undergoing infertility treatment and to describe treatment approaches and clinical outcomes, including transvaginal ultrasound-guided dr…

AIM: To investigate the mechanisms of histone deacetylase (HDAC) 10 inhibitors (HDAC10Is) action in endometriosis and the target molecules of HDAC10Is. METHODS: We assessed the effects of HDAC10Is, tucidinostat and TH34, on the proliferati…

OBJECTIVE: Despite growing recognition of adenomyosis as a significant gynecological condition, standardized hysteroscopic diagnostic criteria remain lacking. This study aimed to systematically characterize endometrial hysteroscopic finding…

AIM: Endometriosis affects 6%-10% of women of reproductive age and is associated with chronic pelvic pain, infertility, and impaired quality of life. The endometriosis fertility index (EFI) predicts spontaneous pregnancy postoperatively, bu…

AIM: This exploratory pilot study aimed to assess the preliminary clinical effects of leuprorelin acetate microspheres for injection [gonadotropin-releasing hormone agonist (GnRH-a)] combined with levonorgestrel-releasing intrauterine syste…

In Japan, the microwave endometrial ablation system (MEA, Microsulis PLC, Waterlooville, UK) is the most widely used device for endometrial ablation and is considered a minimally invasive, uterus-preserving treatment for menorrhagia. Althou…

Borderline ovarian tumors primarily affect younger women and are associated with favorable prognosis, making fertility-sparing surgery a viable option. However, owing to recurrence and malignant transformation risks, careful monitoring is r…

OBJECTIVES: In this study, we aimed to compare the clinical characteristics of cellular leiomyoma (CL) with those of typical uterine leiomyoma (UL) and explore recurrence risk factors in patients with CL myomectomy. STUDY DESIGN: In this re…

Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo-ovarian fistulas associated with endometriosis, highlighting the potential for conservative management i…

PURPOSE: Adenomyosis is a common uterine disease second only to uterine leiomyoma. Its management often requires medical treatment. However, practically no drug has ever been developed exclusively for adenomyosis. Development of non-hormona…

AIM: Endometriosis is a chronic gynecological condition characterized by persistent inflammation and frequently associated with dysmenorrhea and infertility. The success rate of assisted reproductive technology (ART) in individuals with end…

Primary umbilical endometriosis (PUE) is a rare form of extragenital endometriosis, accounting for only 0.5%-1% of all endometriosis cases. Surgical excision is the primary treatment; however, it often results in disfigurement of the umbili…

AIM: Endometriosis is an estrogen-dependent disease with unclear pathogenesis. Recent evidence suggests that ferroptosis plays an important role in the development of endometriosis. In this study, we aimed to explore whether membrane-bound …

Cesarean scar defect (CSD) is a long-term complication of cesarean section (CS). However, its risks for perimenopausal women remain unclear. We present a rare case of CSD involving hematometra in a perimenopausal woman, which led to emergen…

AIM: This study aimed to compare clinical characteristics and evaluate diagnostic biomarkers in ovarian endometriosis, with a focus on thyroid autoimmunity associations. METHODS: A retrospective analysis of 885 patients (441 ovarian endome…

OBJECTIVES: This study investigates iron metabolism characteristics in patients with ovarian endometriosis (EMs) and infertility. METHODS: A case-control study was conducted involving 76 infertility patients treated at Baise People's Hospi…

Seromucinous borderline tumors (SMBTs) generally have a favorable prognosis, and fertility-preserving surgery may be indicated. However, SMBT may occasionally coexist with carcinoma, necessitating careful management. This report presents tw…

AIM: To identify the predictors for periureteral adhesions preoperatively. METHODS: Preoperative predictors for periureteral adhesions were evaluated in 407 patients who underwent laparoscopic hysterectomy (LH) for benign uterine diseases …

BACKGROUND: Endometriosis, affecting ~10% of women of reproductive age, is associated with infertility and adverse pregnancy outcomes. The condition is classified into superficial peritoneal endometriosis (SUP), ovarian endometriomas (OMA),…

AIM: To evaluate pregnancy outcomes by treatment approach and assess the appropriateness and safety of surgical intervention in patients with infertility and uterine adenomyosis. METHODS: A retrospective analysis was conducted on patients,…

Nonsteroidal anti-inflammatory drugs (NSAIDs) are generally avoided in late pregnancy due to fetal risks, such as premature ductus arteriosus closure. However, celecoxib, a selective cyclooxygenase 2 (COX-2) inhibitor, may help manage pain …

PURPOSE: MiRNAs regulate gene expression, impacting reproductive health, such as infertility and implantation failure. This study investigated the association between miRNA polymorphisms and male infertility (azoospermia, oligospermia), fem…