Infertility Treatment of Endometriosis Patients

In: Endometriosis · 2014 · pp. 431–443 · doi:10.1007/978-4-431-54421-0_27 · W58766965
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Infertility treatment for endometriosis patients remains controversial, with surgery showing some benefit for mild disease, ART improving pregnancy rates, and medical treatment not enhancing fertility.

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This chapter reviews evidence on infertility treatment strategies for women with endometriosis, drawing on studies comparing medical therapy, surgery for minimal/mild disease, management of ovarian endometriomas, and assisted reproductive technologies such as IVF and related approaches. The authors report that medical treatment of endometriosis does not improve fertility, while there is some evidence that surgery may help in mild disease; results are conflicting for endometrioma removal because of potential effects on ovarian reserve, and ART improves pregnancy rates but yields lower rates than in women without endometriosis. The chapter emphasizes that optimal decisions (e.g., laparoscopy vs. superovulation with IUI vs. proceeding to ART) depend on factors including age, symptoms, other infertility factors, surgical risks, endometrioma presence, and ovarian reserve, and it notes the variability and conflicting nature of the evidence. This paper is centrally about endometriosis — it specifically summarizes infertility treatment options and their comparative evidence in endometriosis patients.

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Abstract

Endometriosis is common in infertile patients, but infertility treatment of endometriosis patients is controversial and varied. This article summarizes evidence concerning infertility treatment of endometriosis patients. Endometriosis impairs fertility by causing both anatomical and biochemical distortion in female reproductive system. Medical treatment of endometriosis does not improve fertility, whereas there is some evidence that surgery for mild endometriosis does. There is conflicting evidence regarding removal of endometriomas due to the potential impact on ovarian reserve. Assisted reproductive technology (ART) improves pregnancy rates, although the pregnancy rates are lower than for women without endometriosis. Some women with infertility and endometriosis may benefit from a combination of medical treatment, ART, and surgery. The decision about whether to undergo laparoscopy or superovulation (SO) with intrauterine insemination (IUI) or pursue ART will depend on a variety of factors such as the patient’s age and symptoms, other infertility factors, risk of surgery, the presence of endometrioma, and ovarian reserve. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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Author information Authors and Affiliations Corresponding author Editor information Editors and Affiliations Rights and permissions Copyright information © 2014 Springer Japan About this chapter Cite this chapter Koga, K., Yoshino, O., Hirota, Y., Hirata, T., Harada, M., Osuga, Y. (2014). Infertility Treatment of Endometriosis Patients. In: Harada, T. (eds) Endometriosis. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54421-0_27 Download citation DOI: https://doi.org/10.1007/978-4-431-54421-0_27 Published: Publisher Name: Springer, Tokyo Print ISBN: 978-4-431-54420-3 Online ISBN: 978-4-431-54421-0 eBook Packages: MedicineMedicine (R0)

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