Aberrant Expression of Leptin in Human Endometriotic Stromal Cells Is Induced by Elevated Levels of Hypoxia Inducible Factor-1α
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This study investigated the relationship between leptin and hypoxia in endometriosis, finding that elevated hypoxia-inducible factor-1α induces aberrant leptin expression in human endometriotic stromal cells.
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Cited by (50)
- A cRGD-modified liposome for targeted delivery of artesunate to inhibit angiogenesis in endometriosis 2025
- Leptin G2548 A and Leptin Receptor Q223R Gene Polymorphisms are Associated with an Increased Risk of Endometriosis 2025
- Current Understanding of Endometriosis Pathophysiology and Future Perspectives 2025
- Divergent Immune–Metabolic Profiles in Endometriosis and Ovarian Cancer: A Cross-Sectional Analysis 2025
- Oxidative Stress Mediated by Macrophages Promotes Angiogenesis and Early Development of Endometriosis 2024
- Potential Mechanisms of Guizhi Fuling Wan in Treating Endometriosis: An Analysis Based on TCMSP and DisGeNET Databases 2024
- Differential Expression of Insulin Growth Factor 1 (IGF-1) Isoforms in Different Types of Endometriosis: Preliminary Results of a Single-Center Study 2023
- Expression of ZEB1 in different forms of endometriosis: A pilot study 2023
- Vascularisation in Deep Endometriosis: A Systematic Review with Narrative Outcomes 2023
- Downregulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of signal transducer and activator of transcription 1 in endometriosis 2022
- The Role of Platelets in the Pathogenesis of Endometriosis and New Therapeutic Ideas 2022
- Knockdown of miR-150-5p reduces hypoxia-induced autophagy and epithelial-mesenchymal transition of endometriotic cells via regulating the PDCD4/NF-κB signaling pathway 2022
- Endometriosis-Associated Angiogenesis and Anti-angiogenic Therapy for Endometriosis 2022
- Hypoxia activates the unfolded protein response signaling network: An adaptive mechanism for endometriosis 2022
- Hypoxia and immune factors 2021
- miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis 2021
- Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis 2021
- Endometrial epithelial–mesenchymal transition (EMT) by menstruation-related inflammatory factors during hypoxia 2021
- Endometriosis: New Perspective for the Diagnosis of Certain Cytokines in Women and Adolescent Girls, as Well as the Progression of Disease Outgrowth: A Systematic Review 2021
- Molecular and Cellular Changes in the Pathogenesis of Endometriosis 2021
- Immunology and Immunotherapy of Endometriosis 2021
- Platelets induce increased estrogen production through NF-κB and TGF-β1 signaling pathways in endometriotic stromal cells 2020
- Identification of candidate microRNA markers of endometriosis with the use of next-generation sequencing and quantitative real-time polymerase chain reaction 2020
- TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis 2020
- Hyperbaric Oxygen (HBO) Reduce Expression of Hypoxia Inducible Factor-1 Alpha (HIF-1 alpha) and Endometriotic Tissue Size in Mice Model of Endometriosis 2020
- Hypoxia: The force of endometriosis 2019
- The miRNA Mirage: How Close Are We to Finding a Non-Invasive Diagnostic Biomarker in Endometriosis? A Systematic Review 2018
- Pro-endometriotic niche in endometriosis 2018
- Shaofu Zhuyu Decoction Regresses Endometriotic Lesions in a Rat Model 2018
- Long non‐coding <scp>RNA MALAT</scp>1 mediates hypoxia‐induced pro‐survival autophagy of endometrial stromal cells in endometriosis 2018
- Hypoxia, cytokines and stromal recruitment: parallels between pathophysiology of encapsulating peritoneal sclerosis, endometriosis and peritoneal metastasis 2018
- Overexpression of Four Joint Box-I Protein (FJXI) in Eutopic Endometrium From Women With Endometriosis 2017
- The role of TGF-β in the pathophysiology of peritoneal endometriosis 2017
- Epithelial-to-mesenchymal transition in the development of endometriosis 2017
- Hypoxia-inducible factor-1α promotes endometrial stromal cells migration and invasion by upregulating autophagy in endometriosis 2017
- Transforming Growth Factor-beta 1 Involved in the Pathogenesis of Endometriosis through Regulating Expression of Vascular Endothelial Growth Factor under Hypoxia 2017
- Hypoxia‐inhibited DUSP2 expression promotes IL‐6/STAT3 signaling in endometriosis 2017
- Targeting hypoxia‐mediated YAP1 nuclear translocation ameliorates pathogenesis of endometriosis without compromising maternal fertility 2017
- The expression of vascular endothelial growth factor is affected by hypoxia inducible factor-1α in peritoneum of endometriosis mice treated with genistein 2016
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- Nerve fibers and endometriotic lesions: partners in crime in inflicting pains in women with endometriosis 2016
- Elevated Serum CD95/FAS and HIF-1α Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report 2016
- Hypoxia-inducible factor-1alpha: A promising therapeutic target in endometriosis 2016
- Endometriosis and possible inflammation markers 2015
- Deep Quantitative Proteomics Reveals Extensive Metabolic Reprogramming and Cancer-Like Changes of Ectopic Endometriotic Stromal Cells 2015
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- Coordination of AUF1 and miR-148a destabilizes DNA methyltransferase 1 mRNA under hypoxia in endometriosis 2015
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