Peritoneal fluid prostaglandins in various stages of the menstrual cycle: role in infertile patients with endometriosis.
article
OA: closed
CC0
⤵ 35 in-corpus citations
AI-generated summary
Peritoneal fluid prostaglandin F2 alpha and E2 concentrations were significantly higher in endometriosis patients compared to controls, particularly during specific menstrual cycle phases.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Thirty-nine patients with pelvic endometriosis and 45 patients with no evidence of endometriosis were entered in this study. The mean age was 29 years for each group. The volume of peritoneal fluid showed an increase towards the end of the cycle in both groups. Although the volume was higher in the endometriosis group than the control group, the difference between them was not significant. The concentration of prostaglandins F2 alpha and E2 was higher in patients with endometriosis than in the control group. The difference was significant (P less than 0.05) during days 9-16 and 17-24 for both prostaglandins, and during days 1-8 for prostaglandin F 2 alpha only. The high concentration of prostaglandins in the periovulatory and early luteal phases of the cycle may have adverse effects on tubo-ovarian function in endometriosis patients. Prostaglandin studies in peritoneal fluid are of significance during days 9-24 of the cycle when the effect of regurgitated menstrual fluid in the early phase of days 1-8 may be avoided.
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
Cited by (35)
- Clinical features and perinatal outcomes in women with adenomyosis 2025
- Endometriosis Cell Proliferation Induced by Bone Marrow Mesenchymal Stem Cells 2020
- Uterine wall thickness at the second trimester can predict subsequent preterm delivery in pregnancies with adenomyosis 2019
- The role of oxidation-sensitive nociception and epigenetics in endometriosis-associated pain 2017
- Kinase signalling pathways in endometriosis: potential targets for non-hormonal therapeutics 2016
- Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis 2016
- Abnormal Expression of Prostaglandins E2 and F2<i>α</i>Receptors and Transporters in Patients with Endometriosis 2015
- Roles of Prostaglandin E2 in Endometriosis 2014
- Role of prostaglandin E2 in bacterial growth in women with endometriosis 2012
- Tubal Microsurgery versus Assisted Reproduction 2008
- Expression of Inducible Microsomal Prostaglandin E Synthase in Local Lesions of Endometriosis Patients 2007
- Adenomyosis and risk of preterm delivery 2006
- Increased cyclooxygenase-2 expression is associated with better clinical outcome in patients submitted to complete ablation for severe endometriosis 2005
- Analysis of cyclooxygenase-2 (COX-2) expression in different sites of endometriosis and correlation with clinico-pathological parameters 2004
- Entstehung und Pathogenese 2004
- Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis 2001
- Pathophysiology of Endometriosis-Associated Infertility 1999
- Functional and phenotypic alterations in peritoneal macrophages from patients with early and advanced endometriosis 1998
- PATHOPHYSIOLOGY 1997
- PATHOGENESIS OF ENDOMETRIOSIS 1997
- Danazol versus [d-Trp6]GnRH agonist for the management of infertility due to atypical endometriosis 1996
- PGE2 and PGF2α release by human peritoneal macrophages in endometriosis 1996
- The peritoneal environment in endometriosis 1996
- Review of Peritoneal Factors that Affect Fertility in Patients With Mild Endometriosis 1996
- Pathogenesis of Infertility in Endometriosis 1995
- A mid-luteal phase comparison of V76 peritoneal fluid volume and its content of PGF2α and PGE2 in women with minimal stage endometriosis and a normal pelvis 1994
- Changing concepts of medical treatment of endometriosis 1993
- Changes of peripheral blood lymphocyte subsets before and after operation of patients with endometriosis 1993
- Prostaglandins in Dysmenorrhoea and Endometriosis 1992
- The endometrium and endometriosis 1991
- Peritoneal fluid volume and sex steroids in the preovulatory period in mild endometriosis 1991
- The peritoneal environment in endometriosis 1991
- Peritoneal fluid and serum autoantibody levels in patients with endometriosis 1990
- Nafarelin in the treatment of infertility caused by endometriosis 1990
- Uterine contractions in endometriosis: Effects of operative and danazol treatment 1988
Source provenance
- europepmc
- last seen: 2026-06-11T06:19:48.454388+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:09:50.790931+00:00
License: CC0
· commercial use OK