Uterine contractions in endometriosis: Effects of operative and danazol treatment
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Uterine hypercontractility, characterized by increased resting pressure, was observed in women with endometriosis but was unaffected by operative or danazol treatment.
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Abstract
SummaryTo study uterine contractions in proved endometriosis and the effects of operative and danazol treatment, intrauterine pressures at the isthmus and fundus level were recorded 27 times in 17 women with endometriosis and 20 times in 10 healthy women. In endometriosis a pattern of hypercontractility in the form of increased resting pressure was observed both during the luteal phase of the cycle and during menstruation, whereas the frequency of fundal contractions during the luteal phase was decreased. This pattern of uterine contractions was not affected by operative or danazol (600 mg/day) treatment, although these treatments provided symptomatic relief. These data suggest there is uterine hypercontractility in endometriosis, which seems to be of minor importance in causing symptoms.
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Cited by (20)
- Identification of cells without colony-forming ability in Eutopic endometrial progenitor cells in infertile women with endometriosis in comparison with healthy fertile women in Indian perspective 2019
- Uterine peristalsis and fertility: current knowledge and future perspectives: a review and meta-analysis 2017
- Uterine Peristalsis and the Development of Endometriosis and Adenomyosis 2011
- Die Pathophysiologie von Endometriose und Adenomyose. Morphologische, funktionelle und molekularbiologische Grundlagen 2011
- A new concept of endometriosis and adenomyosis: tissue injury and repair (TIAR) 2011
- Endometriosis and adenomyosis – a shared pathophysiology 2010
- The pathophysiology of endometriosis and adenomyosis: tissue injury and repair 2009
- Adenomyosis as a disorder of the early and late human reproductive period 2007
- Adenomyosis in endometriosis – prevalence and impact on fertility. Evidence from magnetic resonance imaging 2006
- Uterotubal transport disorder in adenomyosis and endometriosis—a cause for infertility 2006
- Adenomyosis and reproduction 2006
- Diminished pregnancy rates in endometriosis due to impaired uterotubal transport assessed by hysterosalpingoscintigraphy 2005
- Adenomyosis in endometriosis—prevalence and impact on fertility. Evidence from magnetic resonance imaging 2005
- Uterine Peristaltic Activity and the Development of Endometriosis 2004
- Uterine contractility and directed sperm transport assessed by hysterosalpingoscintigraphy (HSSG) and intrauterine pressure (IUP) measurement 2004
- Dislozierung basalen Endometriums 2003
- Redefining endometriosis: Endometriosis is an entity with extreme pleiomorphism 2000
- Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging 2000
- Endometriosis: a dysfunction and disease of the archimetra 1998
- Menstrual symptoms in women with pelvic endometriosis 1991
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