MRI in the Diagnosis of Endometriosis and Related Diseases

review OA: gold CC0 ⤵ 44 in-corpus citations
AI-generated summary by claude@2026-06, 2026-06-07

MRI effectively diagnoses ovarian endometriotic cysts and deeply infiltrating endometriosis by identifying characteristic T2 hypointense lesions indicative of fibrosis.

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AI-generated deep summary by claude@2026-06, 2026-06-07

This 2022 paper is a review that synthesizes MRI evidence for diagnosing ovarian endometriotic cysts and deeply infiltrating endometriosis (DIE), including how MRI findings relate to lesion location, fibrosis/adhesions, and related physiological or pathological conditions. It describes characteristic ovarian cyst MRI features (e.g., T1-high signal multiplicity, T2-shading, and the T2 dark spot sign) and highlights that for DIE and secondary adhesions, fibrosis around ectopic glands is often seen as T2 hypointense lesions, while noting that the diagnostic value of some sequences (contrast-enhanced T1WI, DWI, susceptibility-weighted imaging) is not recommended specifically for ovarian cysts and DIE in the referenced protocol. A major caveat acknowledged is that diagnosis is ideally confirmed histologically via laparoscopy, and MRI requires specific preparation and protocol choices to optimize detection (including considerations around bladder/vaginal/rectal preparation and motion control). This paper is centrally about endometriosis — it provides a review of MRI findings, optimal imaging protocol, and interpretation for ovarian endometriotic cysts and DIE.

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Abstract

Endometriosis, a common chronic inflammatory disease in female of reproductive age, is closely related to patient symptoms and fertility. Because of its high contrast resolution and objectivity, MRI can contribute to the early and accurate diagnosis of ovarian endometriotic cysts and deeply infiltrating endometriosis without the need for any invasive procedure or radiation exposure. The ovaries, which are the most frequent site of endometriosis, can be afflicted by multiple related conditions and diseases. For the diagnosis of deeply infiltrating endometriosis and secondary adhesions among pelvic organs, fibrosis around the ectopic endometrial gland is usually found as a T2 hypointense lesion. This review summarizes the MRI findings obtained for ovarian endometriotic cysts and their physiologically and pathologically related conditions. This article also includes the key imaging findings of deeply infiltrating endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Female Female Female Female Female Female Humans Humans Humans Humans Humans Humans Magnetic Resonance Imaging

Citation neighborhood

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References (100)

Cited by (44)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-19T00:34:45.133478+00:00
License: CC0 · commercial use OK