Atypical Endometriosis and Malignant Transformation

Helena Heloísa Paixão, Teresa Margarida Cunha
In: Imaging of Endometriosis: A Comparative Guide of US, MRI and Surgery · 2025 · pp. 67–86 · doi:10.1007/978-3-031-82750-1_4 · W4410897519
book-chapter OA: closed CC0
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-06 ⓘ

Radiologic techniques like ultrasound, CT, and MRI are crucial for early detection and characterization of atypical endometriosis and associated cancers.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This chapter reviews the rare transformation of benign endometriosis into endometriosis-associated cancers, noting that atypical endometriosis has been described as a precursor to endometriosis-associated ovarian cancer, particularly endometrioid and clear-cell ovarian carcinomas. It focuses on the pivotal role of imaging—ultrasound, CT, and especially MRI—in the early detection, characterization, and monitoring of atypical endometriosis and related ovarian and extra-ovarian cancers, while emphasizing the challenges of distinguishing benign from potentially malignant disease. The chapter highlights that the underlying physiopathology remains complex and controversial, which limits certainty about mechanisms even as imaging supports diagnostic work. This paper is centrally about endometriosis — it reviews atypical endometriosis and malignant transformation with an emphasis on imaging (US/CT/MRI) for distinguishing benign lesions from endometriosis-associated cancers.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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