Advances in the medical treatment of adolescent endometriosis

Li Yang; Jinfen Yu; Shuang Zhang; Jianya Zhang

doi:10.23736/s2724-5276.21.06375-8

Advances in the medical treatment of adolescent endometriosis

Li Yang, Jinfen Yu, Shuang Zhang, Jianya Zhang

Minerva pediatrics · 2021 · vol. 75(3) , pp. 423–431 · doi:10.23736/s2724-5276.21.06375-8 · PMID:34309341 · W3184476917

article OA: closed CC0 ⤵ 4 in-corpus citations

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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review summarizes medical treatment advances for adolescent endometriosis, detailing drugs that inhibit ectopic lesions and offering guidance for early diagnosis and intervention.

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Abstract

Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus. Adolescent endometriosis is often confined to the pelvic cavity and is a common cause of secondary dysmenorrhea in adolescents. Adolescent endometriosis is often with delayed diagnosis. Early diagnosis and intervention can prevent the damage of pelvic structure and ovarian tissue and reduce the incidence of adhesion and infertility. Adolescent endometriosis can be diagnosed and treated by laparoscopic biopsy. There are many kinds of drugs to treat endometriosis, such as NSAIDs, progesterone, selective progesterone receptor antagonists, GnRH-a, gonadotropin-releasing hormone antagonists, aromatase inhibitors, dopamine agonists, angiogenesis inhibitors, vegetable drugs, traditional Chinese medicine prescriptions. Future treatment options, including Future treatment options include CTZ, vitamin D3, oxytocin receptor inhibitors, melatonin, doxycycline, bevacizumab, curcumin, isotretinoin, and rosiglitazone, etc., can inhibit ectopic lesions. This article mainly summarizes advances in medical treatment underlying adolescent endometriosis and provides guidance for the early clinical diagnosis and intervention of adolescent endometriosis, to improve the quality of life of patients and reduce adverse outcomes.

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Condition tags

dysmenorrheaendometriosisinfertility

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Adolescent Dysmenorrhea Dysmenorrhea Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Hormone Antagonists Hormone Antagonists Humans Quality of Life

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References (76)

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