Atorvastatin causes regression of endometriotic implants in a rat model
article
OA: bronze
CC0
⤵ 39 in-corpus citations
AI-generated summary
In a rat model, atorvastatin treatment effectively reduced the size and number of surgically induced endometriotic implants.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
My notes (saved in your browser only)
Condition tags
MeSH descriptors
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (57)
- Angiogenesis and Macrophage Activation in Endometriosis via openalex
- Angiongenesis: a new theory for endometriosis via openalex
- Antiangiogenesis Therapy for Endometriosis via openalex
- Antiangiogenic Agents Are Effective Inhibitors of Endometriosis via openalex
- Early-stage endometriosis: adhesion and growth of human menstrual endometrium in nude mice via openalex
- Effect of a Statin on an In Vitro Model of Endometriosis via openalex
- Emerging drugs in endometriosis via openalex
- Endometriosis: Treatment Strategies via openalex
- Eutopic endometrium and peritoneal, ovarian and bowel endometriotic tissues express a different profile of matrix metalloproteinases-2, -3 and -11, and of tissue inhibitor metalloproteinases-1 and -2 via openalex
- Evidence for an increased release of proteolytic activity by the eutopic endometrial tissue in women with endometriosis and for involvement of matrix metalloproteinase-9 via openalex
- Evidence for Oxidatively Modified Lipid-Protein Complexes in Endometrium and Endometriosis via openalex
- Extracellular matrix remodelling in the endometrium and its possible relevance to the pathogenesis of endometriosis via openalex
- Focal cellular origin and regulation of interstitial collagenase (matrix metalloproteinase-1) are related to menstrual breakdown in the human endometrium via openalex
- High-dose atorvastatin causes regression of endometriotic implants: a rat model via openalex
- Immunohistochemical assessment of superoxide dismutase expression in the endometrium in endometriosis and adenomyosis via openalex
- Leflunomide—an Immunomodulator—Induces Regression of Endometrial Explants in a Rat Model of Endometriosis via openalex
- Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium via openalex
- Metalloproteinases, vascular endothelial growth factor, and angiopoietin 1 and 2 in eutopic and ectopic endometrium via openalex
- Oxidative stress and peritoneal endometriosis via openalex
- Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex
- Progesterone and transforming growth factor-β coordinately regulate suppression of endometrial matrix metalloproteinases in a model of experimental endometriosis via openalex
- Regression of endometrial explants in a rat model of endometriosis treated with melatonin via openalex
- Simvastatin Protects against the Development of Endometriosis in a Nude Mouse Model via openalex
- Statins Inhibit Growth of Human Endometrial Stromal Cells Independently of Cholesterol Availability1 via openalex
- Suppression of matrix metalloproteinases inhibits establishment of ectopic lesions by human endometrium in nude mice. via openalex
- The relationship between microvessel density, proliferative activity and expression of vascular endothelial growth factor-A and its receptors in eutopic endometrium and endometriotic lesions via openalex
- Vascular endothelial growth factor and the endometrium via openalex
- W2346020725 via openalex
- W4293247451 via openalex
- W6632685685 via openalex
- W2100258830 via openalex
- W1491678226 via openalex
- W1546733625 via openalex
- W1912234690 via openalex
- W1964923339 via openalex
- W1967143550 via openalex
- W1967970013 via openalex
- W1971586374 via openalex
- W1975247881 via openalex
- W1988571789 via openalex
- W1990093374 via openalex
- W1991583073 via openalex
- W1992046768 via openalex
- W1995282459 via openalex
- W2003471941 via openalex
- W2008528615 via openalex
- W2017556192 via openalex
- W2051248001 via openalex
- W2053054955 via openalex
- W2076834039 via openalex
- W293131995 via openalex
- W2108705930 via openalex
- W2115779380 via openalex
- W2125289626 via openalex
- W2128635872 via openalex
- W2132339539 via openalex
- W2143715300 via openalex
Cited by (39)
- Effect of metformin plus statin combination therapy compared to metformin alone in infertile woman with symptomatic endometrioma 2025
- Parthenolide repressed endometriosis induced surgically in rats: Role of PTEN/PI3Kinase/AKT/GSK-3β/β-catenin signaling in inhibition of epithelial mesenchymal transition 2023
- Atorvastatin exerts dual effects of lesion regression and ovarian protection in the prevention and treatment of endometriosis 2023
- Antilipidemic ezetimibe induces regression of endometriotic explants in a rat model of endometriosis with its anti-inflammatory and anti-angiogenic effects 2022
- Effects of metformin, letrozole and atorvastatin on inflammation and apoptosis in experimental peritoneal and ovarian endometriosis in the rat 2022
- Effects of atorvastatin and resveratrol against the experimental endometriosis; evidence for glucose and monocarboxylate transporters, neoangiogenesis 2021
- All-trans retinoic acid inhibits epithelial-to-mesenchymal transition (EMT) through the down-regulation of IL-6 in endometriosis 2021
- Role of medical treatment of endometriosis 2021
- Advances in the medical treatment of adolescent endometriosis 2021
- The Effect of Novel Medical Nonhormonal Treatments on the Angiogenesis of Endometriotic Lesions 2021
- Endometriosis diagnosis and medical treatment: Present and future 2021
- Endometriosis - Review Of Current Therapeutic Aproaches For Disease Control 2019
- Tanshinone IIA contributes to the pathogenesis of endometriosis via renin angiotensin system by regulating the dorsal root ganglion axon sprouting 2019
- Anti‐Angiogenic Alternative and Complementary Medicines for the Treatment of Endometriosis: A Review of Potential Molecular Mechanisms 2018
- Serum MicroRNA Biomarkers Regulated by Simvastatin in a Primate Model of Endometriosis 2018
- Therapeutic Roles of Statins in Gynecology and Obstetrics: The Current Evidence 2018
- Lipophilic statins inhibit growth and reduce invasiveness of human endometrial stromal cells 2018
- Shaofu Zhuyu Decoction Regresses Endometriotic Lesions in a Rat Model 2018
- Current and emerging treatment options for endometriosis 2018
- From pathogenesis to clinical practice: Emerging medical treatments for endometriosis 2018
- Investigational drugs for the treatment of endometriosis, an update on recent developments 2018
- Effect of simvastatin on baboon endometriosis† 2017
- Medical Management of Endometriosis 2017
- A peek into the drug development scenario of endometriosis – A systematic review 2017
- Are matrix metalloproteinases and their inhibitors reliable diagnosis biomarkers and attractive therapeutic targets in endometriosis? 2016
- Treatment of Endometriosis with Non-Hormonal Agents: Review 2016
- Non‐hormonal targets underlying endometriosis: A focus on molecular mechanisms 2015
- Pathogenesis of Endometriosis: Roles of Retinoids and Inflammatory Pathways 2015
- Management of Endometriosis 2015
- Novel Medical Treatment Modalities of Endometriosis 2015
- An overview of early drug development for endometriosis 2015
- Experimental Treatments of Endometriosis 2015
- Statins as Targeted “Magical Pills” for the Conservative Treatment of Endometriosis: May Potential Adverse Effects on Female Fertility Represent the “Dark Side of the Same Coin”? A Systematic Review of Literature 2015
- Novel agents for the medical treatment of endometriosis 2014
- Melatonin causes regression of endometriotic implants in rats by modulating angiogenesis, tissue levels of antioxidants and matrix metalloproteinases 2014
- The genetics and biochemistry of endometriosis 2013
- Medical management of endometriosis: emerging evidence linking inflammation to disease pathophysiology. 2013
- Effects of Simvastatin on Retinoic Acid System in Primary Human Endometrial Stromal Cells and in a Chimeric Model of Human Endometriosis 2013
- Simvastatin Decreases Invasiveness of Human Endometrial Stromal Cells1 2012
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:18.915199+00:00
License: CC0
· commercial use OK