Innovative approach in assessing the role of neurogenesis, angiogenesis, and lymphangiogenesis in the pathogenesis of external genital endometriosis

T Sheveleva, Т. С. Шевелева, Sheveleva T, Bejenar V, V Bejenar, V. F. Bejenar, Э. В. Комличенко, E Komlichenko, Komlichenko E, A Dedul, A. G. Dedul, Dedul A, А. В. Малушко, Malushko A, A Malushko
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2016 · vol. 32(sup2) , pp. 75–79 · doi:10.1080/09513590.2016.1232789 · PMID:27759453 · W2538591211
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This study explored the roles of neurogenesis, angiogenesis, and lymphangiogenesis in the pathogenesis of external genital endometriosis to improve diagnosis and treatment.

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Abstract

Endometriosis is a chronic, progressive, relapsing estrogen-dependent disorder characterized by the growth of tissue structure and function similar to the endometrium outside the normal mucosa of the uterine cavity localization. Endometriosis is found in 10-15% of women in reproductive age and it is one of the main causes of pelvic pain syndrome and infertility. Mechanisms of the development of endometriosis and related pathological pain impulses are still poorly understood and therapeutic approaches do not always have a sufficient effect; in this connection, the study of the pathogenesis of endometriosis and endometriosis-associated pain currently is perspective. Identification of significant factors of angiogenesis, lymphangiogenesis, and neurogenesis in the external genital endometriosis will promote the development of non-invasive early diagnosis and pathogenetic therapy.

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Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Endometriosis Lymphangiogenesis Neovascularization, Physiologic Neurogenesis Endometriosis Female Humans Lymphangiogenesis Neovascularization, Physiologic Neurogenesis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (45)

Cited by (15)

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