Clinical and Medical-History Risk Factors and Immunological Markers for External Genital Endometriosis
This study investigated clinical and medical history risk factors along with immunological markers associated with external genital endometriosis to identify predictive elements.
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This retrospective case–control study evaluated 200 women to identify clinical/medical-history risk factors and immunological markers associated with externally genital endometriosis (EGE), comparing 100 women with laparoscopically verified, histologically confirmed EGE to 100 women undergoing laparoscopy for tubal–peritoneal infertility. Using interviews, medical record analysis, serum steroid measurements and antibody testing, the authors used binary logistic regression to determine the most significant predictors, with thresholds for antibodies derived from ROC analysis. The strongest factors included active and passive smoking, family history of breast cancer, BMI 9 RU) and to progesterone (>8 RU); a major caveat is that the study was retrospective case–control with predictive modeling rather than prospective validation. This paper is centrally about endometriosis — it specifically investigates risk factors and immunological markers for external genital endometriosis.
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References (10)
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- Endometriosis via openalex
- Endometriosis via openalex
- Endometriosis Index: A Software-Derived Score to Predict the Presence and Severity of the Disease via openalex
- Innovative approach in assessing the role of neurogenesis, angiogenesis, and lymphangiogenesis in the pathogenesis of external genital endometriosis via openalex
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- W2618966700 via openalex
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