The prostanoid content in peritoneal fluid and plasma of women with endometriosis

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This study measured prostanoid levels in peritoneal fluid and plasma of women diagnosed with endometriosis to understand their role in the condition.

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Abstract

Peritoneal fluid and plasma collected at laparoscopy in women with and without endometriosis were evaluated for prostanoid content. 6-Keto-prostaglandin F1 alpha (6-keto-F1 alpha), thromboxane B2 (TxB2), 15-keto- 13, 14-dihydroprostaglandin F2 alpha (PGFM), prostaglandin F (PGF) and prostaglandin E (PGE) were assayed in peritoneal fluid, with 6-keto-F1 alpha, TxB2, and PGFM being studied in plasma. The concentrations of these prostanoids in women with endometriosis were not significantly different from the concentrations in the disease-free group, nor was a significant difference seen in any of the prostanoids studied in relationship to the severity of the endometriosis. The results suggest that routine study of prostanoid levels in patients with endometriosis may not be of a diagnostic or prognostic value.

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Prostaglandins Ascitic Fluid Ascitic Fluid Endometriosis Endometriosis Endometriosis Female Female Follicular Phase Follicular Phase Humans Humans Prospective Studies Prospective Studies Prostaglandins Prostaglandins Prostaglandins

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (25)

Cited by (25)

Source provenance

europepmc
last seen: 2026-10-22T06:08:12.857683+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:58:20.576574+00:00
License: CC0 · commercial use OK