Prostaglandin Content of Human Endometrium
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This paper investigated the prostaglandin content of the human endometrium, analyzing its presence and levels within this tissue.
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Abstract
Prostaglandin levels in 46 human endometrium specimens were determined and expressed as both total uterine content and on a dry weight basis. Concentrations of PGF2alpha and PGE did not differ significantly between specimens obtained during the proliferative or secretory phases of the menstrual cycle. There was, however, a fourfold higher total uterine content of prostaglandins during the secretory phase. There was also a more than fourfold higher level of PGF2alpha than of PGE during the secretory phase. The two types of prostaglandins were present in nearly equal amounts during the proliferative phase. Atrophic endometrium was characterized by a high concentration of prostaglandins, but a low total amount consisting of nearly equal amounts of PGF2alpha and PGE.
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Cited by (19)
- Pathophysiology of Endometriosis-Associated Infertility 1999
- Prostaglandins and menstruation 1996
- Prostaglandins and Menstruation 1992
- Eicosanoids production in endometriosis 1992
- Glucocorticoids do not share with progesterone the potent inhibitory action on prostaglandin synthesis in human proliferative phase endometrium 1987
- Prostaglandins, menstruation, and menstrual disorders. 1986
- Endometriosis 1985
- Leiomyomas release prostaglandins 1985
- Endometrial and Myometrial Prostaglandin Release during the Menstrual Cycle in Relation to Menstrual Blood Loss* 1984
- Prostaglandins and Nonsteroidal Antiinflammatory Drugs in Dysmenorrhea 1983
- The prostanoid content in peritoneal fluid and plasma of women with endometriosis 1983
- Prostaglandin secretion by human endometrium in vitro 1982
- PROSTAGLANDIN SYNTHESIS IN THE ENDOMETRIUM OF WOMEN WITH OVULAR DYSFUNCTIONAL UTERINE BLEEDING 1981
- Prostaglandins and their Synthesis Inhibitors in Dysfunctional Uterine Bleeding 1979
- New concepts in dysmenorrhea 1978
- The Use of the Prostaglandin Synthetase Inhibitor Mefenamic Acid in the Treatment of Menorrhagia 1978
- The effect of naproxen-sodium on the prostaglandin concentrations of the menstrual blood and uterine “jet-washings” in dysmenorrehic women 1978
- STUDIES IN THE INVOLVEMENT OF PROSTAGLANDINS IN UTERINE SYMPTOMATOLOGY AND PATHOLOGY 1976
- Plasma Prostaglandin F2 Levels in Dysmenorrheic Women 1976
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