Cul-de-sac fluid in women with endometriosis: fluid volume, protein and prostanoid concentration during the periovulatory period—days 13 to 18

N. Rezai, Rezai N, R B Ghodgaonkar, Ghodgaonkar RB, Ramesh B. Ghodgaonkar, Zacur HA, H A Zacur, Howard A. Zacur, John A. Rock, J A Rock, N H Dubin, Dubin NH, Norman H. Dubin
Fertility and sterility · 1987 · vol. 48(1) , pp. 29–32 · doi:10.1016/s0015-0282(16)59285-1 · PMID:3595914 · W85111144
article OA: closed CC0 ⤵ 13 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study investigated cul-de-sac fluid volume, protein, and prostanoid concentration in women with endometriosis during the periovulatory period (days 13-18).

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Cul-de-sac fluid from women with histologically confirmed endometriosis (n = 45) or from infertile women without evidence of endometriosis (n = 28) was collected at the time of laparoscopy during the periovulatory period (days 13 to 18). This fluid was analyzed for prostaglandin E2 (PGE2), prostaglandin F2a (PGF2a), 13,14-dihydro-15 keto-PGF2a (PGFM), and thromboxane B2 (TXB2) by radioimmunoassay (RIA). Protein content of the fluid also was determined. No difference (P greater than 0.05) in cul-de-sac fluid volume was found between women with and without endometriosis, nor were differences detected in the level of any of the prostanoids measured in fluid from infertile control patients compared with those with endometriosis. This was true regardless of whether the prostanoids were expressed as a concentration, total amount in fluid, or as a ratio of prostanoid to protein content. The present study does not support the theory that cul-de-sac fluid prostanoids provide a useful diagnostic index of endometriosis.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Body Fluids Douglas' Pouch Endometriosis Infertility, Female Menstrual Cycle Prostaglandins Body Fluids Douglas' Pouch Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Ovulation Pregnancy Prostaglandins Proteins Proteins

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (20)

Cited by (13)

Source provenance

europepmc
last seen: 2026-08-22T06:09:51.966504+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:09:30.565292+00:00
unpaywall
last seen: 2026-08-22T06:23:50.750314+00:00
License: CC0 · commercial use OK