John A. Rock

A multicenter collaboration for data collection and statistical analysis may be necessary to establish and validate a classification system based on empirically derived scores for specific pathologic observations. The endometriosis pain ins…

UNLABELLED: This review summarizes current knowledge about the roles of cyclooxygenases and prostaglandins in reproductive medicine. With the development of COX-2 specific inhibitors, new therapeutic options are available to obstetricians a…

ObjectiveTo determine whether retinoic acid (RA) can regulate the expression of interleukin (IL)-6 in human endometrial cells in a manner that might be beneficial to women with endometriosis.DesignIn vitro study.SettingAcademic medical cent…

ObjectiveTo determine the duration of time to the recurrence of pain attributable to endometriosis after the discontinuation of treatment with danazol or a GnRH agonist (GnRH-a) in patients who have had a satisfactory response to the treatm…

In Brief Objective To determine whether the immediate initiation of estrogen replacement therapy (ERT) in the postoperative period increases the incidence of symptom recurrence following total abdominal hysterectomy (TAH) with bilateral sal…

In the 50 years since Sampson1 presented his findings, little has been proven about the pathogenesis of endometriosis. Consequently, our treatment modalities have centered around relief of symptoms. It is difficult to stringently apply the …

Classification systems for endometriosis continue to evolve. Past systems have been modeled primarily after those in use for grading malignant disease. Unfortunately, classification methods that attempted to quantitate the severity of disea…

ObjectiveTo review the use of radiotherapy for relieving the symptoms of recurrent endometriosis caused by functioning ovarian remnants.DesignRetrospective study (case report).Patient(s)A woman with recurrent endometriosis of 14 years' dura…

ObjectiveTo determine the incidence, clinical stage, and lesion type of endometriosis in adolescent girls.DesignRetrospective review of patient records of adolescent girls (11-19) admitted to Emory University Affiliated Hospitals.SettingPat…

OBJECTIVES: To determine the relative risk of symptom recurrence and/or reoperation after hysterectomy with ovarian preservation for the treatment of endometriosis. DESIGN: Historical prospective study of patients with endometriosis who un…

Studies reveal endometriosis to be present in 38-51% of women undergoing laparoscopy for chronic pelvic pain. Symptoms attributable to endometriosis include dysmenorrhea, dyspareunia, generalized pelvic pain, dyschezia, and radiation of pai…

OBJECTIVE: To determine the effects of regular exercise on women receiving danazol for the treatment of endometriosis. METHODS: Thirty-nine patients were randomized to a danazol-only or a danazol/exercise regimen in a prospective clinical t…

OBJECTIVE: To assess the reproducibility in staging endometriosis using the revised American Fertility Society (AFS) classification of endometriosis. DESIGN: Visual documentation of laparoscopies of 315 women with endometriosis was scored …

Fifteen patients with a history of endometriosis and recurrent pelvic pain underwent conservative resection at laparotomy. Microsurgical resection of endometriotic lesions and restoration of pelvic anatomy were performed. Presacral neurecto…