Treatment of Endometriosis

Reddy S, S Reddy, Sujatha Reddy, J A Rock, John A. Rock
Clinical Obstetrics and Gynecology · 1998 · vol. 41(2) , pp. 387–392 · doi:10.1097/00003081-199806000-00020 · PMID:9646971 · W2329122967
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The pathogenesis of endometriosis remains poorly understood, necessitating individualized symptom-relief treatments due to the scarcity of randomized controlled trials and varied patient presentations.

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This brief editorial by Reddy and Rock reviews the historical context of endometriosis treatment, noting that despite Sampson’s findings fifty years prior, the pathogenesis remains largely unproven. The authors argue that current therapeutic strategies focus primarily on symptom relief due to a lack of rigorous evidence-based studies and the heterogeneous nature of patient symptoms. They emphasize that uniform treatment algorithms are impossible to implement, necessitating customized care plans tailored to individual reproductive needs. This paper is centrally about endometriosis — specifically discussing the challenges in developing standardized treatment protocols for the condition.

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Abstract

In the 50 years since Sampson1 presented his findings, little has been proven about the pathogenesis of endometriosis. Consequently, our treatment modalities have centered around relief of symptoms. It is difficult to stringently apply the principles of evidence-based medicine to this enigmatic disease because few randomized placebocontrolled studies have been published. The varied symptoms make uniform treatment algorithms impossible to follow. Treatment must be customized to each patients' symptoms and reproductive needs.
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Articles Treatment of Endometriosis - SUJATHA REDDY - JOHN A. ROCK Clinical Obstetrics & Gynecology 41(2):p 387-392, June 1998. In the 50 years since Sampson presented his findings, little has been proven about the pathogenesis of endometriosis. Consequently, our treatment modalities have centered around relief of symptoms. It is difficult to stringently apply the principles of evidence-based medicine to this enigmatic disease because few randomized placebocontrolled studies have been published. The varied symptoms make uniform treatment algorithms impossible to follow. Treatment must be customized to each patients' symptoms and reproductive needs. Copyright © Lippincott-Raven Publishers

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Danazol Danazol Drug Therapy, Combination Endometriosis Endometriosis Endometriosis Estrogen Antagonists Estrogen Antagonists Estrogens Estrogens Estrogens Evidence-Based Medicine Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Hysterectomy Progesterone Progesterone Progesterone

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (17)

Cited by (8)

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