Epithelial localization of antiendometrial antibodies associated with endometriosis

Wild RA, R A Wild, Robert A. Wild, Satyaswaroop PG, P G Satyaswaroop, Shivers AC, A C Shivers, ALEX C. SHIVERS
American journal of reproductive immunology and microbiology : AJRIM · 1987 · vol. 13(2) , pp. 62–65 · doi:10.1111/j.1600-0897.1987.tb00092.x · PMID:2438953 · W1587626585
Other OA: closed CC0 ⤵ 20 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-28 ⓘ

Antiendometrial antibodies in endometriosis sera selectively bind to the epithelial component of normal endometrium, not the stromal component.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Antiendometrial antibodies have been demonstrated in patients with endometriosis. As a further step in understanding the immunological alterations against the endometrium, isolated glandular and stromal monolayer endometrial cell preparations and endometrial, breast, and ovarian carcinoma cell lines were tested by indirect immunofluorescence assay utilizing sera of patients with endometriosis previously shown to have antibodies against endometrium. In dilutions of serum of 1:1 to 1:16, significant fluorescence staining was noted only in the glandular (epithelial) component and not in the stromal component of normal endometrium without regard to phase of the menstrual cycle. The significance of this finding as it relates to the pathophysiology of endometriosis awaits further study.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Antibodies Endometriosis Endometrium Antibodies Antibodies Antibodies Autoantibodies Autoantibodies Autoantibodies Cell Line Cell Line Endometriosis Endometriosis Endometriosis Endometrium Endometrium Epithelium Epithelium Epithelium Epitopes

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (20)

Cited by (20)

Source provenance

europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-10-08T21:13:06.373426+00:00
unpaywall
last seen: 2026-10-14T06:23:58.021457+00:00
License: CC0 · commercial use OK