Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest

Salvatore Caruso, S Caruso, M Iraci, S Cianci, Stefano Cianci, E Casella, V Fava, Valentina Fava, A Cianci, Antonio Cianci
Journal of endocrinological investigation · 2015 · vol. 38(11) , pp. 1211–1218 · doi:10.1007/s40618-015-0383-7 · PMID:26337183 · W1579364324
article OA: closed CC0 ⤵ 51 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-06 ⓘ

Dienogest treatment improved pain, quality of life, and sexual function in women with endometriosis-associated pelvic pain compared to non-steroidal anti-inflammatory drugs.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 ⓘ

This study evaluated effects of dienogest (DNG) on quality of life and sexual function in 54 women with endometriosis-associated pelvic pain, with 48 women receiving non-steroidal anti-inflammatory drugs as a control group. Pain was tracked using the Visual Analogic Scale, while QoL, sexual function, and sexual distress were assessed using SF-36, FSFI, and FSDS at 3 and 6 months; the study explicitly notes a limitation in that it includes only these two follow-up timepoints. DNG treatment improved pain at 3 months (p < 0.05) and more strongly at 6 months (p < 0.001), with QoL improving in all SF-36 categories by 6 months (p < 0.001), while FSFI showed no change at 3 months but increased by 6 months (p < 0.05), alongside a decrease in FSDS by 6 months (p < 0.001). The paper does explicitly discuss endometriosis; it is centrally about endometriosis — assessing how dienogest treatment affects quality of life and sexual function in women with endometriosis-associated pelvic pain.

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Condition tags

mesh:D004715mesh:D017699endometriosis

MeSH descriptors

Hormone Antagonists Nandrolone Orgasm Pelvic Pain Quality of Life Sexual Behavior Adolescent Adult Endometriosis Endometriosis Female Follow-Up Studies Hormone Antagonists Hormone Antagonists Humans Nandrolone Nandrolone Nandrolone Orgasm Pelvic Pain

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