Sexual function and sexual quality of life in women affected by endometriosis and adenomyosis compared to healthy women

Rasekh Jahroomi A, Athar Rasekh Jahroomi, Mohammadi S, Solmaz Mohammadi, Noorozi Z, Zahra Noorozi, Khani S, Sara Khani, S H Gharah Khani, Afsaneh Ranjbar, Ranjbar A, Vahid Rahmanian, Rahmanian V, Jamali S, Safieh Jamali, Aryan Khani, Khani A, A Ramezan Khani
Women & health · 2025 · vol. 65(9) , pp. 802–812 · doi:10.1080/03630242.2025.2580459 · PMID:41213818 · W4416675650
article OA: closed CC0 ⤵ 1 in-corpus citation
Full text JSON View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

Women with endometriosis and adenomyosis exhibited significantly lower sexual function and quality of life compared to healthy controls, with predictors including desire, arousal, pain, marriage age, and relationship satisfaction.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-07, 2026-07-17 · read from full text ⓘ

This 2022–2023 cross-sectional comparative study recruited 90 women from clinics in Iran, including 30 with endometriosis, 30 with adenomyosis, and 30 healthy controls, and assessed sexual function, sexual quality of life, and relationship satisfaction using the SQOL-F and FSFI questionnaires plus the RAS questionnaire. Women with endometriosis and adenomyosis reported significantly lower sexual quality of life and sexual function scores than controls, with p < 0.0001. Univariate and regression analyses identified sexual function components and relationship factors as predictors of sexual quality of life, while marriage age and relationship duration were negative predictors, and the model explained 36.5% of variance; a key limitation is the cross-sectional design, which does not establish causality. This paper is centrally about endometriosis and adenomyosis—comparing their impacts on sexual function and sexual quality of life versus healthy women.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Adenomyosis and endometriosis are chronic gynecological disorders with overlapping mechanisms and symptoms, both linked to impaired sexual health and relationships. This study compared sexual function, sexual quality of life, and relationship satisfaction in affected women and healthy controls. This cross-sectional comparative study (2022-2023) included 90 women in three groups: endometriosis (n = 30), adenomyosis (n = 30), and healthy controls (n = 30), recruited from Jahrom University clinics in Iran. Participants completed the SQOL-F.FSFI, and RAS questionnaires. Data were analyzed with ANOVA and regression (SPSS 25, p < 0.05). Women with endometriosis (21.8 ± 3.8; 95% CI: 20.5-23.2; 19.3 ± 2.9; 95% CI: 18.3-20.4; 42.3 ± 8.9; 95% CI: 39.2-45.5) and adenomyosis (23.2 ± 4.6; 95% CI: 21.6-24.9; 19.3 ± 3.0; 95% CI: 18.2-20.4; 49.7 ± 11.0; 95% CI: 45.8-53.7) had significantly lower scores than controls (26.6 ± 4.8; 95% CI: 24.9-28.3; 22.2 ± 3.5; 95% CI: 20.9-23.4; 51.5 ± 12.3; 95% CI: 47.1-55.9; p < 0.0001). Univariate analysis showed sexual function, desire, and arousal were positive, and pain negative, predictors of sexual quality of life. Regression indicated marriage age and duration were negative, while spouse's age, sexual function, and relationship satisfaction were positive predictors, explaining 36.5% of variance.Endometriosis and adenomyosis significantly reduce sexual function and quality of life. Counseling and supportive care are recommended to address these challenges.
Full text 2,839 characters · extracted from oa-doi-fallback · click to expand
ABSTRACT Adenomyosis and endometriosis are chronic gynecological disorders with overlapping mechanisms and symptoms, both linked to impaired sexual health and relationships. This study compared sexual function, sexual quality of life, and relationship satisfaction in affected women and healthy controls. This cross-sectional comparative study (2022–2023) included 90 women in three groups: endometriosis (n = 30), adenomyosis (n = 30), and healthy controls (n = 30), recruited from Jahrom University clinics in Iran. Participants completed the SQOL-F.FSFI, and RAS questionnaires. Data were analyzed with ANOVA and regression (SPSS 25, p < 0.05). Women with endometriosis (21.8 ± 3.8; 95% CI: 20.5–23.2; 19.3 ± 2.9; 95% CI: 18.3–20.4; 42.3 ± 8.9; 95% CI: 39.2–45.5) and adenomyosis (23.2 ± 4.6; 95% CI: 21.6–24.9; 19.3 ± 3.0; 95% CI: 18.2–20.4; 49.7 ± 11.0; 95% CI: 45.8–53.7) had significantly lower scores than controls (26.6 ± 4.8; 95% CI: 24.9–28.3; 22.2 ± 3.5; 95% CI: 20.9–23.4; 51.5 ± 12.3; 95% CI: 47.1–55.9; p < 0.0001). Univariate analysis showed sexual function, desire, and arousal were positive, and pain negative, predictors of sexual quality of life. Regression indicated marriage age and duration were negative, while spouse’s age, sexual function, and relationship satisfaction were positive predictors, explaining 36.5% of variance.Endometriosis and adenomyosis significantly reduce sexual function and quality of life. Counseling and supportive care are recommended to address these challenges. Acknowledgments The authors thank all the women who participated in this project and we would like to appreciate the officials and staff of the Jahrom Clinic and all those who helped us in this study. Disclosure statement No potential conflict of interest was reported by the author(s). Author contributions All the authors contributed to the conception and design of the study. SJ and AKH were involved in writing the article, while ZN, SM, and AR participated in data collection. VR, AR, and SKH were responsible for the statistical analysis of the project. All authors read and approved the final manuscript. Data availability statement The original contributions presented in the study can be directed to the corresponding author. Ethics statement The studies involving human participants were reviewed and approved by the Research Ethics Committee of Jahrom University (Reference code: IR.JUMS.REC.1401.015). The research project was also approved by Jahrom University of Medical Sciences (Project Code: 400,000,212). All participants provided written informed consent; participation was voluntary, and confidentiality was maintained in accordance with the Declaration of Helsinki. Correction Statement This article has been corrected with minor changes. These changes do not impact the academic content of the article.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisadenomyosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (27)

Cited by (1)

Source provenance

europepmc
last seen: 2026-08-03T06:10:56.557307+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-08-03T06:06:52.095223+00:00
License: CC0 · commercial use OK