{"paper_id":"a18095b0-5d25-457e-9977-d3fa4f6da5da","body_text":"ABSTRACT\nAdenomyosis and endometriosis are chronic gynecological disorders with overlapping mechanisms and symptoms, both linked to impaired sexual health and relationships. This study compared sexual function, sexual quality of life, and relationship satisfaction in affected women and healthy controls. This cross-sectional comparative study (2022–2023) included 90 women in three groups: endometriosis (n = 30), adenomyosis (n = 30), and healthy controls (n = 30), recruited from Jahrom University clinics in Iran. Participants completed the SQOL-F.FSFI, and RAS questionnaires. Data were analyzed with ANOVA and regression (SPSS 25, p < 0.05). Women with endometriosis (21.8 ± 3.8; 95% CI: 20.5–23.2; 19.3 ± 2.9; 95% CI: 18.3–20.4; 42.3 ± 8.9; 95% CI: 39.2–45.5) and adenomyosis (23.2 ± 4.6; 95% CI: 21.6–24.9; 19.3 ± 3.0; 95% CI: 18.2–20.4; 49.7 ± 11.0; 95% CI: 45.8–53.7) had significantly lower scores than controls (26.6 ± 4.8; 95% CI: 24.9–28.3; 22.2 ± 3.5; 95% CI: 20.9–23.4; 51.5 ± 12.3; 95% CI: 47.1–55.9; p < 0.0001). Univariate analysis showed sexual function, desire, and arousal were positive, and pain negative, predictors of sexual quality of life. Regression indicated marriage age and duration were negative, while spouse’s age, sexual function, and relationship satisfaction were positive predictors, explaining 36.5% of variance.Endometriosis and adenomyosis significantly reduce sexual function and quality of life. Counseling and supportive care are recommended to address these challenges.\nAcknowledgments\nThe authors thank all the women who participated in this project and we would like to appreciate the officials and staff of the Jahrom Clinic and all those who helped us in this study.\nDisclosure statement\nNo potential conflict of interest was reported by the author(s).\nAuthor contributions\nAll the authors contributed to the conception and design of the study. SJ and AKH were involved in writing the article, while ZN, SM, and AR participated in data collection. VR, AR, and SKH were responsible for the statistical analysis of the project. All authors read and approved the final manuscript.\nData availability statement\nThe original contributions presented in the study can be directed to the corresponding author.\nEthics statement\nThe studies involving human participants were reviewed and approved by the Research Ethics Committee of Jahrom University (Reference code: IR.JUMS.REC.1401.015). The research project was also approved by Jahrom University of Medical Sciences (Project Code: 400,000,212). All participants provided written informed consent; participation was voluntary, and confidentiality was maintained in accordance with the Declaration of Helsinki.\nCorrection Statement\nThis article has been corrected with minor changes. These changes do not impact the academic content of the article.","source_license":"CC0","license_restricted":false}