Endometriosis and atherosclerosis: what we already know and what we have yet to discover

L. Santoro, Luca Santoro, D'Onofrio F, Ferruccio D'Onofrio, Ferruccio D’Onofrio, Roberto Flore, Antonio Gasbarrini, Gasbarrini A, Angelo Santoliquido
American journal of obstetrics and gynecology · 2015 · vol. 213(3) , pp. 326–331 · doi:10.1016/j.ajog.2015.04.027 · PMID:25935777 · W1964863313
review OA: closed CC0 ⤵ 24 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This review synthesizes existing knowledge on the relationship between endometriosis and atherosclerosis, highlighting areas requiring further investigation to understand their potential connection.

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Abstract

The possible association between endometriosis and atherosclerosis represents an emerging topic in the field of women's health. In this Clinical Opinion paper, we analyze this theme focusing on the pathogenetic mechanisms of both diseases, deeply discussing about what is already known about this association and producing starting points about what we consider suitable to research in the near future with regard to cardiovascular involvement in women affected by endometriosis. We have identified 5 reports specifically carried out to investigate the relationship between atherosclerosis and endometriosis; these studies show the presence of subclinical atherosclerosis in women affected by endometriosis, susceptible of regression after surgical removal of endometriosis, with a possible prognostic relevance for variations of cardiovascular risk in these women. However, to date, no studies in literature have been carried out to investigate the real incidence of cardiovascular events in women with endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Atherosclerosis Endometriosis Asymptomatic Diseases Atherosclerosis Atherosclerosis Atherosclerosis Cardiovascular Diseases Cardiovascular Diseases Carotid Intima-Media Thickness Endometriosis Endometriosis Endothelium, Vascular Endothelium, Vascular Female Humans Remission Induction Risk Factors Treatment Outcome Vascular Stiffness Vascular Stiffness

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (52)

Cited by (26)

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europepmc
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openalex
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License: CC0 · commercial use OK