Proteomic analysis of peritoneal fluid in women with endometriosis

Simone Ferrero, Gillott DJ, David J. Gillott, Valentino Remorgida, Paola Anserini, Kit-Yi Leung, Kit‐Yi Leung, Leung KY, Ragni N, Nicola Ragni, Grudzinskas JG, J. G. Grudzinskas, Jurgis G Grudzinskas
Journal of proteome research · 2007 · vol. 6(9) , pp. 3402–3411 · doi:10.1021/pr060680q · PMID:17676783 · W1987300601
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This study analyzed peritoneal fluid proteomes using electrophoresis and mass spectrometry, identifying aberrant protein expressions in women with endometriosis that may reveal disease pathogenesis.

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Abstract

This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Proteomics Adult Adult Ascitic Fluid Ascitic Fluid Chromatography, Liquid Chromatography, Liquid Electrophoresis, Gel, Two-Dimensional Electrophoresis, Gel, Two-Dimensional Electrophoresis, Gel, Two-Dimensional Endometriosis Endometriosis Female Female Humans Humans Hydrogen-Ion Concentration Hydrogen-Ion Concentration

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (44)

Cited by (35)

Source provenance

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License: CC0 · commercial use OK