Proteomic Analysis of Peritoneal Fluid in Women with Endometriosis

Simone Ferrero, David J Gillott, Valentino Remorgida, Paola Anserini, Kit-Yi Leung, Kit‐Yi Leung, Nicola Ragni, Jurgis G Grudzinskas, J. G. Grudzinskas
Journal of proteome research · 2007 · vol. 6(9) , pp. 3402–3411 · doi:10.1021/pr060680q · PMID:17676783 · W1987300601
article OA: closed CC0 ⤵ 36 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study analyzed peritoneal fluid proteomes using electrophoresis and mass spectrometry, identifying aberrant protein expressions in women with endometriosis that may reveal disease pathogenesis.

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Abstract

This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease. Keywords: endometriosis • peritoneal fluid • tandem mass spectrometry • proteomics • two-dimensional gel electrophoresis

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Condition tags

endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Proteomics Adult Ascitic Fluid Chromatography, Liquid Electrophoresis, Gel, Two-Dimensional Electrophoresis, Gel, Two-Dimensional Endometriosis Female Humans Hydrogen-Ion Concentration Mass Spectrometry Mass Spectrometry Menstrual Cycle Proteomics Silver Staining

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (44)

Cited by (36)

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