The pathology of endometriosis

Fox H, Henrik Fox, H. Fox
Irish journal of medical science · 1983 · vol. 152(S2) , pp. 9–13 · doi:10.1007/bf02945274 · PMID:6885323 · W2164883541
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-15 ⓘ

This paper examines the pathology of endometriosis by reviewing literature on its origins, clinical characteristics, hormonal influences, and associations with infertility and malignancy.

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This paper is a narrative overview by Fox, H., summarizing the pathology of endometriosis and drawing on a broad set of prior clinical, experimental, immunologic, hormonal, receptor, and ultrastructural findings to describe theories of origin, lesion behavior, and possible malignant transformation. It synthesizes evidence spanning topics such as hormonal regulation of implants, prostaglandin involvement, coelomic metaplasia and implantation concepts, familial and immune associations, and the histogenesis/spread of endometriosis, using predominantly literature-based evidence rather than new experiments. A key limitation is that, as a review-style account, it does not present original data or a systematic method for evaluating the included studies. This paper is centrally about endometriosis — it specifically reviews the pathological basis, origins, and lesion biology of endometriosis.

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Gynecol. 60, 1147. Weed, J. C. and Arquembourg, P. C. 1980. Endometriosis: can it producean autoimmune response resulting in infertility?Clin. Obstet. Gynec. 23, 885. Willman, E. A., Collins, W. P. and Clayton, S. G. 1976. Studies in the involvement of prostaglandins in uterine symptomatology and pathology.Brit J. Obstet. Gynaec. 83. 337. Young, S., Moon, D. V. M., Leung, P. C. S., Yuen, B. H. and Gomel, V. 1981. Prostaglandin F in human endometriotic tissue.Amer. J. Obstet. Gynec. 141, 344. Author information Authors and Affiliations Rights and permissions About this article Cite this article Fox, H. The pathology of endometriosis. Ir J Med Sci 152 (Suppl 2), 9–13 (1983). https://doi.org/10.1007/BF02945274 Issue date: DOI: https://doi.org/10.1007/BF02945274

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Pelvic Neoplasms Endometriosis Endometriosis Endometriosis Female Genital Neoplasms, Female Genital Neoplasms, Female Humans Infertility, Female Infertility, Female Neoplasm Staging Pelvic Neoplasms

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